Tue.Jan 21, 2025

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HDL Antioxidant Function Diminished in Patients with HFpEF, Study Finds

HCPLive

Increases in oxidized HDL levels were linked to HFpEF in new analyses, suggesting reduced antioxidant HDL function is present in this patient population.

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Microplastics in Water; New NCD for CardioMEMS; Valve Surgery Amid Los Angeles Fires

Med Page Today

(MedPage Today) -- A study showed that microplastics -- small enough to pass into human blood and organs -- were found in tap and bottled water in France. (PLOS Water) Artificial intelligence (AI) enabled non-experts to produce high-quality.

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Brelovitug Receives FDA Breakthrough Therapy Designation for Chronic Hepatitis Delta

HCPLive

The Breakthrough Therapy designation comes just months after positive phase 2 data for brelovitug were presented at AASLD The Liver Meeting in 2024.

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Yellowish Nodules on a Man Consuming a Carnivore Diet

JAMA Cardiology

This case report describes a diagnosis of xanthelasma in a man in his 40s who adopted a carnivore diet 8 months before presentation.

Diet 104
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Mindfulness Reduces Cravings in OUD, No Impact on Abstinence

HCPLive

Mindfulness eased opioid cravings in OUD patients on buprenorphine but showed no added benefit over recovery support for abstinence, substance use, or anxiety.

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Good Response to Obesity Treatment in Childhood Improved Outcomes Down the Line

Med Page Today

(MedPage Today) -- Beneficial pediatric obesity treatment response was associated with a reduced risk of obesity-related events in young adults, a nationwide prospective cohort study in Sweden showed. Compared with poor response, good response.

Obesity 97
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Air Pollution, Climate Change Exacerbate COPD, Asthma

HCPLive

Meteorological conditions effect on exacerbations were likely mediated by particulate matter.

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More Trending

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JAKi Treatment for Psoriatic Arthritis Not Associated With Increased CVD, VTE, Cancer Risk

HCPLive

Cancer risk was examined for breast, colorectal, lung, and prostate cancer.

Cancer 105
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Heart and harmony: A guide to healthy traditions for Lunar New Year

Medical Xpress - Cardiology

For millions of Asians and Asian American people, the Lunar New Year, which begins in 2025 on January 29, is an annual time of renewal, reflection and traditions that promote health and longevity. This year, the celebrations lead directly into American Heart Month, an opportunity to focus on heart health and well-being. As the world's leading nonprofit organization focused on heart and brain health for all, the American Heart Association is proud to support families in living a prosperous new ye

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Outcomes of Asymptomatic Transthyretin Cardiac Amyloid Infiltration

JAMA Cardiology

This cohort study characterizes the clinical phenotype and natural history of asymptomatic patients with transthyretin cardiac amyloid infiltration.

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Why is obesity linked to irregular heart rhythms? Researchers found one potential mechanism

Medical Xpress - Cardiology

Atrial fibrillation, or A-fib, is an irregular heart rhythm that increases a person's risk of stroke, heart failure and even premature death.

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Patient Factors Influence Semaglutide Initiation After Obesity Diagnosis

HCPLive

Approximately 2.0% of commercially insured individuals with obesity, but not diabetes, initiated semaglutide within 6 months of diagnosis.

Obesity 72
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Age-dependent effects of SGLT2 inhibitors on stroke risk in geriatric patients with diabetes and atrial fibrillation

Cardiovascular Diabetology

Atrial fibrillation (AF) and diabetes mellitus (DM) are associated with an increased risk of ischemic stroke, particularly in geriatric populations. Sodium-glucose cotransporter-2 inhibitors (SGLT2i) have demo.

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Acute Dyspnea in a Dialysis Patient. K is 6.3 mEq/L. Are ECG findings due to hyperkalemia, or even due to Type 2 MI?

Dr. Smith's ECG Blog

I was reading ECGs on the system and saw all of these, from one patient. I read them without clinical context and looked at the clinical context later. A 70-something dialysis patient presented and coronary disease had missed dialysis and then presented with acute onset of shortness of breath. He denied chest pain. There was mild hypoxia prehospital, lowest saturation 90%, On arrival, BP was 140/84, pulse 122, O2sat 100% and the patient had increased work of breathing.

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Association of sodium–glucose cotransporter-2 inhibitors with mortality across the spectrum of myocardial infarction: a systematic review and meta-analysis

Cardiovascular Diabetology

The impact of sodiumglucose cotransporter-2 (SGLT2) inhibitors on mortality following myocardial infarction (MI) remains uncertain. Additionally, the role of type 2 diabetes mellitus (T2DM) and heart failure.

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Multimodality Imaging in Pericardial Diseases and the Role of Imaging-Guided Therapies

American College of Cardiology

Pericardial diseases represent the second-most common cause of emergency department and acute care visits for chest pain.

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Association of estimated glucose disposal rate with metabolic syndrome prevalence and mortality risks: a population-based study

Cardiovascular Diabetology

Insulin resistance (IR) is a central pathophysiological factor in metabolic syndrome (MetS) and an essential driver of cardiovascular disease (CVD) and mortality. The estimated glucose disposal rate (eGDR) is.

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An AI Model Applied to ECG Images Can Predict HF Risk

American College of Cardiology

A novel artificial intelligence (AI) model applied to a 12-lead electrocardiogram (ECG) image was able to identify individuals at elevated risk of heart failure (HF) across multinational cohorts without HF at baseline, according to a study published Jan. 13 in European Heart Journal.

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Anti-ETAR, Anti-CXCR3 Antibodies Linked to IgA Nephropathy, Lupus Nephritis Prognosis

HCPLive

Study findings point to the prognostic value of anti-ETAR and anti-CXCR3 antibodies in IgA nephropathy and lupus nephritis.

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Temporal order of atrial fibrillation and acute myocardial infarction and associated prognosis in the Danish Diet, Cancer and Health cohort

Open Heart

Background Atrial fibrillation (AF) and acute myocardial infarction (AMI) share risk factors and are bidirectionally associated. Several studies found higher risks of outcomes in individuals with both conditions. Whether the risks of outcomes differ according to temporal order of AF and AMI is unclear. Methods The study was based on the Danish Diet, Cancer and Health cohort.

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Dupilumab Effective for Pediatric Patients with Atopic Dermatitis at 16 Weeks

HCPLive

These real-life data highlight dupilumabs efficacy at 16 weeks, with the safety and effectiveness in children with atopic dermatitis continuing to 52 weeks.

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An approach to fluoroless radiofrequency atrial fibrillation ablation

Frontiers in Cardiovascular Medicine

Atrial fibrillation is the most prevalent arrhythmia with a lifetime risk of nearly 30%. It can be associated with reduced quality of life and complications such as heart failure and stroke. Pulmonary vein isolation (PVI) is the most effective treatment for rhythm control. It has initially been performed with fluoroscopic catheter guiding. The advent of three-dimensional (3D) electro-anatomical mapping has significantly reduced the need for fluoroscopy.

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Antimicrobials, Vaccinations, Anti-inflammatories Linked to Lower Dementia Risk

HCPLive

A study showed that vitamins, supplements, and antipsychotics were associated with an increased dementia risk.

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U of California Health saves $15M with cardiac surgery consortium

Becker's Hospital Review - Cardiology

The University of California's five medical centers have collected and pooled cardiac surgery data for more than a decade, allowing the system to streamline care and improve financial margins. Subsequent data analysis has resulted in 132 bed days saved and a financial margin improvement of about $15 million.

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FDA Approves Esketamine as First Monotherapy for Treatment-Resistant Depression

HCPLive

The FDA approved esketamine (SPRAVATO) nasal spray as the first monotherapy for adults with TRD, showing rapid efficacy at 4 weeks.

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Epigallocatechin gallate (EGCG) modulates senescent endothelial cell-monocyte communication in age-related vascular inflammation

Frontiers in Cardiovascular Medicine

Aging significantly affects intercellular communication between vascular endothelial cells (ECs) and hematopoietic cells, leading to vascular inflammation and age-associated diseases. This study determined how senescent ECs communicate with monocytes, whether extracellular vesicles (EVs) released from senescent ECs affect monocyte functions, and investigated the potential for epigallocatechin-3-gallate (EGCG), a flavonoid in green tea, to reverse these effects.

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ACCEL Lite: The Role of Advanced Lipid Testing in 2024 

American College of Cardiology

In this interview, Drs. Laxmi Mehta and Michael Shapiro discuss the role and importance of advanced lipid testing.

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Clinical burden of obstructive hypertrophic cardiomyopathy in France

Frontiers in Cardiovascular Medicine

BackgroundHypertrophic cardiomyopathy (HCM) can be genetic and occurs as obstructive and non-obstructive 21 subtypes. Little is known about the clinical burden of the obstructive subtype of HCM at a national 22 level, and how it may differ by New York Heart Association (NYHA) class. Therefore, this study 23 aimed to describe the clinical burden of patients hospitalized with obstructive HCM from a 24 nationwide study in France.MethodsThis retrospective, longitudinal, observational study was perfo

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Large-Bore Mechanical Thrombectomy or Catheter-Directed Thrombolysis For Management of Intermediate-High–Risk Pulmonary Embolism

American College of Cardiology

Acute pulmonary embolism (PE) remains a diagnostic and therapeutic challenge, with an estimated 60,000-100,000 deaths each year in the United States.

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Atherogenic index of plasma and coronary artery disease: a systematic review and meta-analysis of observational studies

Cardiovascular Diabetology

Atherogenic index of plasma (AIP), a novel logarithmic index that combines fasting triglyceride and high-density lipoprotein cholesterol concentrations, is associated with the burden of atherosclerosis. This s.

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Overweight, Obesity in Patients With HeFH Contribute to Higher ASCVD Risk

American College of Cardiology

Overweight and obesity are common in patients with heterozygous familial hypercholesterolemia (HeFH) and are associated with a greater risk of atherosclerotic cardiovascular disease (ASCVD) starting in childhood and regardless of LDL-C level and lipid-lowering medication, according to a cross-sectional analysis published Jan. 13 in the European Heart Journal.

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Effect of neuromuscular electrical stimulation combined with respiratory rehabilitation training on pulmonary rehabilitation in patients with chronic obstructive pulmonary disease

Journal of Cardiothoracic Surgery

the study aimed to analyze the therapeutic effects of neuromuscular electrical stimulation (NMES) combined with respiratory muscle training (RMT) on patients with moderate-to-severe chronic obstructive pulmona.

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Digital Twins Accurately Detect Substrate Abnormalities in VT Ablation

American College of Cardiology

Personalized heart digital twin models accurately detect substrate and functional abnormalities during ablation for scar-dependent ventricular tachycardia (VT).

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Systolic blood pressure response during exercise testing in symptomatic severe aortic stenosis

Open Heart

Aims Exercise testing remains underused in patients with aortic stenosis (AS), partly due to concerns about an exercise-induced drop in systolic blood pressure (SBP). We aimed to study the SBP response to exercise in patients with severe symptomatic AS prior to surgery and 1 year postoperatively. Methods Patients scheduled for aortic valve replacement due to severe symptomatic AS were enrolled at a single centre in a prospective observational cohort study.

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9 heart centers opening, expanding in 2025

Becker's Hospital Review - Cardiology

"Discover the latest heart openings and expansions, including new cardiac electrophysiology services and recovery centers, from top healthcare institutions acro

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Artificial intelligence-based, non-invasive assessment of the central aortic pressure in adults after operative or interventional treatment of aortic coarctation

Open Heart

Background Aortic coarctation (CoA) is a congenital anomaly leading to upper-body hypertension and lower-body hypotension. Despite surgical or interventional treatment, arterial hypertension may develop and contribute to morbidity and mortality. Conventional blood pressure (BP) measurement methods lack precision for individual diagnoses and therapeutic decisions.

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Where US hospitals stand on value of heart attack care: 5 things to know

Becker's Hospital Review - Cardiology

The majority of U.S. hospitals meet the national average of mortality and payment rates used to calculate value of care for heart attack patients, according to CMS data published Oct. 30, 2024.