Tue.Nov 26, 2024

article thumbnail

Brain Volume Changes Come 10 Years Sooner for Men With Cardiovascular Risks

Med Page Today

(MedPage Today) -- Men at high risk of cardiovascular disease had brain volume changes a decade earlier than women, U.K. Biobank data showed. Cardiovascular risk and obesity had the strongest relationship with lower gray matter volume in men between.

Obesity 111
article thumbnail

Can Antipsychotics Increase Mortality Risk? A New Study Shows It Might

HCPLive

A study showed high-dose antipsychotics and benzodiazepines were linked to an increased mortality risk for those with schizophrenia. High-dose antidepressants lowered the risk.

105
105
article thumbnail

World's most common heart valve disease linked to insulin resistance in large national study

Science Daily - Heart Disease

A large new population study of men over 45 indicates insulin resistance may be an important risk factor for the development of the world's most common heart valve disease -- aortic stenosis (AS).

article thumbnail

The link between sleep and blood pressure: New research sheds light on gender differences

Medical Xpress - Cardiology

You may have heard sleep described as something of a magic pill for the body. With the right amount, timing, and quality, it can work wonders—strengthen the immune system, improve blood sugar, even decrease the risk of heart attacks and strokes. Sleep differences have been reported for some time in men and women, but it is not well known whether the characteristics of sleep serve different functions in one gender over the other, especially as it relates to the heart.

article thumbnail

Hunting & Heart Attacks; Cardiologist's Whistleblower Suit; Algorithm Predicts Death

Med Page Today

(MedPage Today) -- The American Heart Association said that hunters should be advised that physical exertion, colder temperatures, and the thrill of the hunt can put them at risk for heart attack or stroke. Merck announced positive topline results.

article thumbnail

The link between sleep and blood pressure: New research sheds light on gender differences

Science Daily - Heart Disease

You may have heard sleep described as something of a magic pill for the body. With the right amount, timing, and quality, it can work wonders -- strengthen the immune system, improve blood sugar, even decrease the risk of heart attacks and strokes. Sleep differences have been reported for some time in men and women, but it is not well known whether the characteristics of sleep serve different functions in one gender over the other, especially as it relates to the heart.

article thumbnail

Emory hospital 1st in US to transplant magnet heart pump

Becker's Hospital Review - Cardiology

An Atlanta-based Emory University Hospital team became the first in the U.S. to perform a surgical implantation of magnetically levitated ventricular assist device.

More Trending

article thumbnail

FDA Accepts Alnylam’s sNDA for Vutrisiran for ATTR-CM

HCPLive

The FDA set the Prescription Drug User Fee Act (PDUFA) date for the investigational RNAi therapeutic as March 23, 2025.

111
111
article thumbnail

Researchers reprogram skin cells to create human-compatible pig heart valve

Medical Xpress - Cardiology

Human skin cells have been reprogrammed into heart valve cells and then used to successfully transplant a pig heart valve into a rodent, led by the research of a Northeastern University professor.

article thumbnail

Many Drinkers Cut Back After Starting Obesity Meds, Study Finds

Med Page Today

(MedPage Today) -- Nearly half of participants in a weight-loss program who consumed alcohol at baseline began drinking less after adding an obesity drug into their weight-management regimen, a cohort study indicated. Among the 7,491 participants.

Obesity 72
article thumbnail

Consensus on Platelet Function and Genetic Testing in PCI: Key Points

American College of Cardiology

The following are key points to remember from a 2024 updated international consensus statement on platelet function and genetic testing in percutaneous coronary intervention (PCI).

Article 75
article thumbnail

Managing Drug-Drug Interactions with Mavacamten: a Focus on Combined Use of Anti-Arrhythmic Drugs and Anticoagulants

HeartRhythm

Mavacamten is a selective, allosteric, and reversible cardiac myosin inhibitor, representing the first disease-specific treatment for obstructive hypertrophic cardiomyopathy (HCM) that targets the core pathophysiological mechanism of this condition. Clinical evidence supports its efficacy in improving symptoms, cardiac function and remodeling, thereby supplementing established treatment regimes.

article thumbnail

Healing the gut can reduce long-term impact of stroke

Science Daily - Stroke

Healing the gut may be the key to improving long-term recovery in stroke patients, scientists have found. The latest of multiple studies highlights the potential of this novel avenue of treatment, which takes advantage of the link between the brain and digestive system to curb cognitive impairment and other lingering impacts of a stroke or brain trauma.

Strokes 69
article thumbnail

Recovery of testing for heart disease risk factors post-COVID remains patchy

Science Daily - Heart Disease

Routine screening to detect risk factors for heart disease dropped sharply during the COVID-19 pandemic in England, and some key measurements, such as blood pressure readings, may still lag behind pre-pandemic levels, according to a new study.

article thumbnail

Study Shows Many with Treatment-Resistant Schizophrenia Have a Poor Diet

HCPLive

A study demonstrates many people with treatment-resistant schizophrenia do not comply with nutritional recommendations, which can contribute to increased mortality risk.

Diet 64
article thumbnail

Ablation as First-Line Treatment in Tolerated VT and LVEF >35%

American College of Cardiology

What are the outcomes of patients referred for ventricular tachycardia (VT) ablation according to left ventricular ejection fraction (LVEF), tolerance of VT, and acute ablation outcome?

article thumbnail

Link Identified Between Obesity, Inflammatory Skin Diseases Such as Psoriasis

HCPLive

The investigators of this study noted an association between obesity and conditions such as rosacea, psoriasis, and lichen simplex chronicus.

Obesity 64
article thumbnail

STS 2025 Coding Workshop

Society of Thoracic Surgeons - Allied Health

Event STS 2025 Coding Workshop gmckinney Tue, 11/26/2024 - 10:25 Event dates Feb 28 – Mar 1, 2025 Location Virtual Register Now Early Bird registration deadline: Jan. 17 Description The STS 2025 Coding Workshop: Best Practices for Cardiothoracic Surgery is a 2-day virtual event that provides coders, surgeons, and billing professionals with the latest updates to CPT and physician coding and reimbursement.

article thumbnail

Obesity Drug MariTide Achieves Up to 20% Weight Loss in Phase 2 Trial

HCPLive

Amgen’s MariTide achieved up to 20% average weight loss at 52 weeks without hitting a plateau in individuals with obesity or overweight.

Obesity 64
article thumbnail

AHA: Variation seen in rates of SGLT2i rx for heart failure, LVEF >40 percent

Medical Xpress - Cardiology

From 2021 to 2023, there was an increase in prescription rates of a sodium-glucose cotransporter-2 inhibitor (SGLT2i) for patients with heart failure and a left ventricular ejection fraction (LVEF) greater than 40 percent, according to a study published online Nov. 18 in JAMA Cardiology to coincide with the American Heart Association Scientific Sessions 2024, held from Nov. 16 to 18 in Chicago.

article thumbnail

The interaction between triglyceride-glucose index and visceral adiposity in cardiovascular disease risk: findings from a nationwide Chinese cohort

Cardiovascular Diabetology

Globally, cardiovascular disease (CVD) constitutes the primary cause of death, with insulin resistance (IR), measured by the triglyceride-glucose (TyG) index, and visceral obesity, reflected by the Chinese Vis.

article thumbnail

Clinical application of standardization right thoracic incision for thoracoscopic thymic tumor resection

Journal of Cardiothoracic Surgery

With the continuous development of minimally invasive thoracic surgery, thoracoscopic thymectomy has become a routine operation. This method, now widely recognized, better protects lung function, reduces intra.

article thumbnail

ECG analysis of ventricular fibrillation dynamics reflects ischaemic progression subject to variability in patient anatomy and electrode location

Frontiers in Cardiovascular Medicine

BackgroundVentricular fibrillation (VF) is the deadliest arrhythmia, often caused by myocardial ischaemia. VF patients require urgent intervention planned quickly and non-invasively. However, the accuracy with which electrocardiographic (ECG) markers reflect the underlying arrhythmic substrate is unknown.MethodsWe analysed how ECG metrics reflect the fibrillatory dynamics of electrical excitation and ischaemic substrate.

Anatomy 52
article thumbnail

GLP-1s reduced risk of major cardiac event by 13%: 5 things to know

Becker's Hospital Review - Cardiology

GLP-1 medications reduced the risk of major adverse cardiovascular events by 13% compared to a placebo, according to a study published Nov. 25 in The Lancet Diabetes & Endocrinology.

article thumbnail

Lactate metabolism and lactylation in cardiovascular disease: novel mechanisms and therapeutic targets

Frontiers in Cardiovascular Medicine

Cardiovascular disease (CVD) is responsible for approximately 30% of annual global mortality rates, yet existing treatments for this condition are considered less than ideal. Despite being previously overlooked, lactate, a byproduct of glycolysis, is now acknowledged for its crucial role in the cellular functions of the cardiovascular system. Recent studies have shown that lactate influences the proliferation, differentiation, and activation of immune cells through its modulation of post-transla

article thumbnail

Overview of Stool DNA Test for CRC

HCPLive

Vivek Kaul, MD, discusses the benefits of using a stool DNA test for colorectal cancer screening, emphasizing its sensitivity, guideline recommendations, and its potential to reduce the screening burden for patients, as well as explaining the test's mechanism of action.

Cancer 52
article thumbnail

Differences between echocardiography and cardiac nuclear magnetic resonance parameters in children with bicuspid aortic valve-related aortopathy

Frontiers in Cardiovascular Medicine

ObjectivesThe bicuspid aortic valve (BAV) is the most common congenital heart defect. Patients with BAV frequently develop aortopathy, which depends on the dysfunction and morphotype of the BAV.AimThe aim of our study was to compare the echocardiography and cardiac magnetic resonance (CMR) findings in BAV patients, and to define the risks of BAV dysfunction and aortopathy.MethodsThe retrospective study included 50 patients (68% male) with BAV, with an average age of 13.6 ± 3.9 years, who underwe

article thumbnail

Gideon Hirshfield, FRCP, PhD: Developing Therapies to Address Pruritus in PBC

HCPLive

Hirschfield describes the need for therapies that address itch in PBC and explains what linerixibat, an IBAT inhibitor, may offer for pruritus.

59
article thumbnail

Do CVD Events Precede a Diagnosis of T2D?

American College of Cardiology

Individuals with type 2 diabetes (T2D) experienced two-fold more cardiovascular disease events than matched comparisons in the general population as much as 30 years before their diagnosis of T2D, according to results from a large, contemporary, nationwide registry-based study published Nov. 25 in JACC.

article thumbnail

What Are the Concerns of Patients with Aspirin-Exacerbated Respiratory Disease?

HCPLive

In this segment of the latest Lungcast episode, the characteristics of AERD and the concerns of patients were highlighted.

64
article thumbnail

CathPCI Registry: Safety and Feasibility of IVL as a Treatment For In-Stent Restenosis

American College of Cardiology

Use of intravascular lithotripsy (IVL) for the treatment of in-stent restenosis (ISR), although off-label, may be safe and feasible, according to a study reviewing data from the ACC's CathPCI Registry published in JACC: Cardiovascular Interventions.

Stents 46
article thumbnail

Pavel Strnad, MD: The Underlying Molecular Mechanisms of PI*ZZ AATD Liver Disease

HCPLive

Strnad reviews findings from a proteomic analysis about AATD-associated liver disease and how they may aid future disease monitoring and drug development.

52
article thumbnail

ACCEL Lite: Top Takeaways from 2024: CV Imaging with Thomas H. Marwick, MD, PhD, FACC

American College of Cardiology

In this interview, Thomas H. Marwick, MD, PhD, FACC, and Alison L. Bailey, MD FACC, discuss the Top Takeaways from 2024 in Cardiovascular (CV) Imaging. Dr. Marwick discusses the SCOT-HEART trial, patient-echo reports augmented by AI, tricuspid valve regurgitation, and more.

article thumbnail

Pilot study shows cryoablation is safe and effective for cardiac repair in patients with atrial fibrillation

Medical Xpress - Cardiology

New research shows that cryoablation is a safe and effective approach to close congenital patent foramen ovale (PFO, a small hole in the heart) in patients with atrial fibrillation (AF) undergoing pulmonary vein isolation (PVI) in a single procedure.

article thumbnail

Unexpected Response to a Common Pacing Maneuver During Tachycardia

HeartRhythm

A 70-year-old male underwent an electrophysiologic (EP) study for episodic palpitations. Baseline HV interval was 54 msec. Atrial extra stimulus testing induced a short- RP tachycardia initiated by prolongation of the AH interval. The response of the tachycardia to ventricular overdrive pacing (VOP) from the right ventricular (RV) apex is shown in figure 1A and the response to atrial overdrive pacing (AOP) is shown in figure 1B.

article thumbnail

Recovery of testing for heart disease risk factors post-COVID remains patchy, say researchers

Medical Xpress - Cardiology

Routine screening to detect risk factors for heart disease dropped sharply during the COVID-19 pandemic in England, and some key measurements, such as blood pressure readings, may still lag behind pre-pandemic levels.

article thumbnail

Cardiac magnetic resonance feature tracking reveals abnormalities in patients with idiopathic ventricular fibrillation

HeartRhythm

The cause of sudden cardiac arrest remains undefined in approximately 5% of patients, the latter receiving the diagnosis of ‘idiopathic ventricular fibrillation’ (IVF). Unraveling the mechanisms underlying the arrest is a clinical need for these often young patients who may be negatively impacted by uncertainties about their prognosis, including the risk for recurrences.1 By definition, IVF patients lack specific structural abnormalities.