CardiacWire
APRIL 18, 2025
Building stronger evidence for AIs place in cardiology, this week brought several examples of how AI can improve ECG use cases and automate Echo for new disease detection methods. Starting with AI improving ECG for coronary revascularization , a deep learning ECG model outperformed both clinician-led ECG and troponin T testing in predicting which ED patients needed coronary revascularization.
Stroke Journal
APRIL 18, 2025
Stroke, Ahead of Print. BACKGROUND:Stroke often results in significant impairments across various domains, including movement, language, cognition, and mood. Neurostimulants have been proposed as potential therapeutic interventions to enhance recovery in these areas.METHODS:This narrative literature review examines clinical trials investigating the efficacy of neurostimulants in poststroke recovery.
Cardiometabolic Health Congress
APRIL 18, 2025
World Liver Day 2025 | A Global Call to Action for Liver Health through Nutrition A global coalition of leading health organizations unites to mark World Liver Day on Saturday, April 19, emphasizing the pivotal role of nutrition in supporting liver function and preventing disease. With the theme Food is Medicine, the campaign urges the global community to take action through sustainable lifestyle changes.
HCPLive
APRIL 18, 2025
Dupilumab's approval marks the first new, targeted therapy for CSU in more than a decade and is the 7th indication for a disease with underlying type 2 inflammation.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Med Page Today
APRIL 18, 2025
(MedPage Today) -- The Supreme Court will hear oral arguments Monday in a case that could affect what kind of preventive care is covered at no charge under Americans' health insurance plans. The case, known as Kennedy v. Braidwood, involves Christian.
HCPLive
APRIL 18, 2025
Greenspan offers tips in treating seasonal allergies in patients with pulmonary conditions, such as long-COVID, and provides his 2025 spring allergy prediction.
Cardiovascular Update brings together the best content for cardiovascular medicine professionals from the widest variety of industry thought leaders.
HCPLive
APRIL 18, 2025
This interview in the latest issue of The Respiratory Report features Divay Chandra, MD, MSc, discussing lithium's potential enhancement of alveolar repair after injury.
American College of Cardiology
APRIL 18, 2025
Patients who undergo catheter ablation for atrial fibrillation (AFib) who also have heart failure with preserved ejection fraction (HFpEF) experienced a greater benefit from ablation in terms of clinical outcome, AFib recurrence and functional status, according to findings from the CABANA trial.
HCPLive
APRIL 18, 2025
Divay Chandra, MD, MSc, University of Pittsburgh, is evaluating whether higher circulating lithium levels are associated with emphysema in a new study.
American College of Cardiology
APRIL 18, 2025
Patients with chronic kidney disease (CKD), including those with end-stage renal disease (ESRD) on dialysis, are at high risk of developing cardiovascular disease (CVD).
HCPLive
APRIL 18, 2025
This interview in the latest issue of The Respiratory Report features William Zhang, MD, discussing AM iron accumulation, which may contribute to the well-known phenomenon of AM dysfunction in COPD6.
American College of Cardiology
APRIL 18, 2025
Leading up to the fourth High-Level Meeting of the United Nations General Assembly (UNGA) on the Prevention and Control of Noncommunicable Diseases (NCDs) in September, a new report from the NCD Alliance offers an overview of the challenges and opportunities associated with optimizing the health care workforce to meet global NCD goals.
HCPLive
APRIL 18, 2025
Anemia can moderate the association between both conditions, increasing the risk of atherosclerotic cardiovascular disease.
The New England Journal of Medicine
APRIL 18, 2025
As the fossil-fuel industry continues to obstruct efforts to curtail pollution from its products, the health community should use strategies that have been effective in fighting other health-harming industries.
HCPLive
APRIL 18, 2025
Class 3 obesity conferred the greatest risk of mortality, complications, and higher resource utilization in alcohol-associated hepatitis hospitalizations.
Hypertension Journal
APRIL 18, 2025
Hypertension, Ahead of Print. BACKGROUND:Hypertension and advanced age are risk factors for arteriosclerotic cerebral small vessel disease (cSVD), a common cause of vascular dementia in elderly individuals. Circulating IGF-1 (insulin-like growth factor 1) levels decrease with age and are linked to age-related cognitive impairment. This study assessed the relationship between serum IGF-1 and arteriosclerotic cSVD severity in patients and the therapeutic effects and underlying mechanisms of exogen
HCPLive
APRIL 18, 2025
In this summary, we highlight the latest issue of our pulmonology research quarterly newsletter powered by the American Lung Association Research Institute.
Hypertension Journal
APRIL 18, 2025
Hypertension, Ahead of Print. BACKGROUND:Sympathetic deactivation represents a major goal of antihypertensive drug treatment. However, whether treatment normalizes the hypertension-related sympathetic cardiovascular overdrive remains uncertain.METHODS:In 219 middle-aged essential hypertensives, we analyzed, along with office systolic and diastolic blood pressure (BP) and heart rate, muscle sympathetic nerve traffic (MSNA, microneurography) before and after 3-month treatment, either as monotherap
HCPLive
APRIL 18, 2025
Label updates simplify twice-yearly echo monitoring for eligible patients in the maintenance phase and expand eligibility with reduced contraindications.
Journal of the American Heart Association
APRIL 18, 2025
Journal of the American Heart Association, Ahead of Print.
HCPLive
APRIL 18, 2025
Without estrogen, the skin barrier weakens, leading to more severe and symptomatic psoriasis.
NEJM Journal Watch - Cardiology
APRIL 18, 2025
Bleeding was associated strongly with cancer diagnoses at the site of bleeding.
HCPLive
APRIL 18, 2025
The FDA identified no issues with the safety or efficacy of aflibercept 8 mg in any of its already approved dosing regimens or indications.
Journal of Cardiovascular Electrophysiology
APRIL 18, 2025
ABSTRACT Background Data on sex-related outcomes of pulmonary vein isolation (PVI) of cryoballoon ablation (CBA) in atrial fibrillation (AF) are sparse. Aim To compare sex-differences in PV reconnection, strategy and outcome of repeat ablations after CBA. Methods Repeat procedures were performed using radiofrequency ablation guided by 3D mapping. PV reconnection characteristics were compared in 229 patients (77 (33.6%) females).
HCPLive
APRIL 18, 2025
Anti-IL-17 medications meant to treat psoriasis and psoriatic arthritis may inadvertently harm gastrointestinal tract.
Dr. Paddy Barrett
APRIL 18, 2025
As a cardiologist, I get asked all the time, “ How much exercise should I do?” My answer is always the same. “You are asking the wrong question.” Generally, this response is met with a blank stare. Let me explain. The question you really need to ask is: “What are my exercise goals, and am I doing enough to hit them?” Or more scientifically, what are the three metrics I need to achieve to maximally improve my odds of longevity.
HCPLive
APRIL 18, 2025
Experts discuss how data from studies like JADE EXTEND, Heads Up Extension, and LEVEL UP, showing improved outcomes with JAK inhibitors in patients who failed biologic therapy, influence their clinical practice and decision-making when considering switching systemic therapies for patients with atopic dermatitis.
Stroke Journal
APRIL 18, 2025
Stroke, Ahead of Print. Atrial fibrillation is a frequent cardiac arrhythmia and is associated with an increased risk of cardioembolic stroke. The left atrial appendage is a finger-like extension originating from the main body of the left atrium and the main location of thrombus formation in patients with atrial fibrillation. Surgical or percutaneous left atrial appendage occlusion (LAAO) aims at preventing clot formation in the left atrial appendage.
HCPLive
APRIL 18, 2025
A panelist discusses how they determine the appropriateness of a Janus kinase (JAK) inhibitor for patients by evaluating disease severity, duration, prior treatment failures, patient comorbidities, risk factors, and laboratory results and engaging in detailed benefit-risk discussions while setting realistic expectations about treatment outcomes and potential adverse effects.
Physiologically Speaking
APRIL 18, 2025
Greetings! Welcome to the Physiology Friday newsletter. Quick correction: My first LIVE Subscriber Q&A session will occur next Friday, April 25 at 2:45 pm CST/3:45 EST. Sorry for the confusion in the previous email. Details about the sponsors of this newsletter including FSTFUEL electrolytes, Examine.com , and my book “VO2 Max Essentials ” can be found at the end of the post.
HCPLive
APRIL 18, 2025
Experts discuss how clinical judgment guides the decision to increase the dose of a JAK inhibitor, considering factors like patient response and symptom severity, and how often dose escalation is implemented in practice based on individual patient needs.
Stroke Journal
APRIL 18, 2025
Stroke, Ahead of Print. BACKGROUND:Neonatal hypoxic-ischemic (HI) brain injury is one of the leading causes of long-term neurological morbidity in newborns. Current treatment options for HI brain injury are limited, but mesenchymal stem cell (MSC) therapy is a promising strategy to boost neuroregeneration after injury. Optimization strategies to further enhance the potential of MSCs are under development.
HCPLive
APRIL 18, 2025
Experts discuss key takeaways for dermatologists managing atopic dermatitis with JAK inhibitors, emphasizing the importance of individualized treatment plans, monitoring for safety and efficacy, and balancing the benefits of JAK inhibitors with potential risks, especially in long-term use.
Journal of Cardiovascular Electrophysiology
APRIL 18, 2025
High-frequency low-tidal volume (HFLTV) ventilation is a safe and cost-effective strategy that improves the efficiency and efficacy of radiofrequency catheter ablation (RFCA) for paroxysmal and persistent atrial fibrillation (PAF/PeAF). Our study aimed to assess the effect of HFLTV-ventilation plus rapid-atrial pacing (RAP) during RFCA of PAF on procedural and long-term clinical outcomes compared to HFLTV-ventilation alone.
HCPLive
APRIL 18, 2025
Peter Miller, MD, PhD, from Massachusetts General Hospital and Harvard Medical School, is working to further uncover the role of clonal hematopoeisis in COPD.
Clinical Trial Results
APRIL 18, 2025
Dr. Merhran and I discuss the HOST-BR trial (optimal DAPT duration for high or low bleeding risk), ECLIPSE trial (orbital atherectomy vs. balloon angioplasty for calcified coronary lesions), BHF PROTECT-TAVI trial (cerebral embolic protection for stroke prevention after TAVI), FLAVOUR II trial (angioFFR vs. IVUS for guiding PCI), and ACC.25 experience.
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