Med Page Today
JUNE 5, 2025
(MedPage Today) -- Older adults taking GLP-1 receptor agonists, primarily semaglutide (Rybelsus, Ozempic, Wegovy), had a small uptick in their risk of developing neovascular age-related macular degeneration (nAMD), according to a retrospective.
Medical Xpress - Cardiology
JUNE 5, 2025
For over a decade, scientists have been growing organoids—small clusters of cells that mimic a particular organ—to serve as miniature biological models. Organoids of the brain have been used to study neurodevelopmental disorders; intestinal organoids, to model celiac disease; and lung organoids, to investigate SARS-CoV-2. Heart organoids have even been sent to space to test the effect of microgravity on cardiac muscle.
Med Page Today
JUNE 5, 2025
(MedPage Today) -- An SGLT2 inhibitor combined with a nonsteroidal mineralocorticoid receptor antagonist quickly cut urinary albumin-to-creatinine ratio (UACR) in patients with albuminuria and both chronic kidney disease (CKD) and type 2 diabetes.
HCPLive
JUNE 5, 2025
Combination therapy with finerenone and empagliflozin significantly reduces urinary albumin levels in CKD patients.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Society of Thoracic Surgeons - Congenital
JUNE 5, 2025
Press Release Surgical Ablation During CABG Linked to Improved Survival in Patients with Preexisting Atrial Fibrillation June 4, 2025 KCummings Thu, 06/05/2025 - 12:56 CHICAGO (June 4, 2025) — A new study published in The Annals of Thoracic Surgery, a journal from The Society of Thoracic Surgeons, finds that Medicare patients with atrial fibrillation (AF) who undergo surgical ablation during isolated coronary artery bypass grafting (CABG) live longer than those who do not, offering compelling su
Nature Reviews - Cardiology
JUNE 5, 2025
Nature Reviews Cardiology, Published online: 06 June 2025; doi:10.1038/s41569-025-01178-3 Cardiac resynchronization therapy is used to treat dyssynchronous heart failure. Lead-related complications and anatomical constraints can limit pacing lead placement, but leadless systems are now becoming available. These new systems overcome lead-related issues, offering a new option for patients with complex disease (such as congenital heart disease) by eliminating intravascular hardware.
Cardiovascular Update brings together the best content for cardiovascular medicine professionals from the widest variety of industry thought leaders.
Cardiovascular Diabetology
JUNE 5, 2025
Orforglipron, a novel oral, non-peptide glucagon like peptide-1 (GLP-1) receptor agonist, has demonstrated efficacy in improving body weight reduction and glycemic control. However, its potential benefits in i.
HCPLive
JUNE 5, 2025
UK study finds atopic conditions, especially anaphylaxis, significantly raise the risk of anxiety, depression, OCD, and other mental illnesses in primary care patients.
Cardiovascular Diabetology
JUNE 5, 2025
Cardiometabolic multimorbidity (CMM), characterized by the co-existence of two or more cardiometabolic diseases (CMDs) including type 2 diabetes (T2D), coronary artery disease (CAD), and stroke, persists as a.
HCPLive
JUNE 5, 2025
GLP-1 RAs, one of the most common medications for obesity and diabetes, have several inherent risks that are often overlooked in favor of their efficacy.
DAIC
JUNE 5, 2025
tim.hodson Thu, 06/05/2025 - 15:03 June 5, 2025 – Penumbra, Inc. has announced the U.S. Food and Drug Administration (FDA) clearance and launch of the Ruby XL System, the longest, largest and softest coil on the market [i]. The Ruby XL System is designed to help physicians achieve more efficient embolization, potentially reducing radiation exposure, and optimizing outcomes — especially in large vessel and high-flow embolization [ii].
Frontiers in Cardiovascular Medicine
JUNE 5, 2025
Tetralogy of Fallot (ToF) is a chronic hypoxic condition that increases the risk of inflammatory responses during surgery. However, many inflammatory biomarkers used to predict surgical outcomes are costly and not widely accessible. This single-center, retrospective observational study aimed to compare the prognostic value of neutrophil-lymphocyte ratio (NLR), absolute lymphocyte count (ALC), and thrombocyte-lymphocyte ratio (TLR) in predicting outcomes of ToF primary repair.
Journal of the American Heart Association
JUNE 5, 2025
Journal of the American Heart Association, Ahead of Print. BackgroundAlthough previous studies have suggested that left ventricular ejection fraction (LVEF) adjusted by left ventricular mass (LVM) might improve prognostic risk stratification of cardiac events, few prospective cohort studies have examined its clinical implications. We assessed the predictive ability of LVEF indexed to LVM, body surface area (BSA), and body mass index for the cardiac event risk.MethodsWe conducted a 5.52‐year coho
Circulation
JUNE 5, 2025
Circulation, Ahead of Print. BACKGROUND:Recent studies have highlighted the deleterious role of high phosphate intake in hypertension by means of sympathetic overactivation, yet the underlying mechanisms remain unclear. Dietary phosphate loading triggers physiologic release of FGF23 (fibroblast growth factor–23) from the bone to maintain phosphate homeostasis.
Journal of the American Heart Association
JUNE 5, 2025
Journal of the American Heart Association, Ahead of Print. BackgroundRivaroxaban is a first‐line agent for venous thromboembolism prophylaxis and treatment. However, its pharmacokinetics, pharmacodynamics, and bleeding risk exhibit significant interindividual variability. Known nongenetic factors alone cannot fully explain this variability, and the impact of genetic polymorphisms remains debated.MethodsFrom December 29, 2021, to May 11, 2023, 310 patients with venous thromboembolism treated with
HeartRhythm
JUNE 5, 2025
Left bundle branch area pacing (LBBAP) has emerged as the leading form of conduction system pacing.1 Initially performed using lumenless leads with fixed helixes like the SelectSecure 3830 (Medtronic),1 it has expanded across all major cardiac rhythm management companies, enabled by the development of dedicated delivery sheaths and relabeling of existing leads for use in the LBB region.
Journal of the American Heart Association
JUNE 5, 2025
Journal of the American Heart Association, Ahead of Print. BackgroundPathways for single‐ventricle palliation include traditional neonatal surgical stage 1 palliation (SP), hybrid stage 1 palliation (HP; pulmonary artery flow restriction with ductal stenting), and delayed surgical stage 1 palliation (DSP), preceded by pulmonary artery flow restriction and prostaglandins.
HCPLive
JUNE 5, 2025
The rheumatology month in review emphasizes new research in gout burden, fibromyalgia management, and innovative lupus treatments.
Cassling
JUNE 5, 2025
Diversity, equity and inclusion (DEI) have become central themes in the modern healthcare environment. DEI is a framework that companies use to create a safe and welcoming space where employees have equal opportunities regardless of background. Its far more than race or gender and takes into account national origin, generational difference, disability, religion, military status and more.
HCPLive
JUNE 5, 2025
Investigators compared the medications across various patient cohorts with different causes of anemia, finding evidence almost uniformly in favor of FCM.
Journal of the American Heart Association
JUNE 5, 2025
Journal of the American Heart Association, Ahead of Print. BackgroundMultiple valvular heart disease correlates with poor outcomes following transcatheter aortic valve replacement. Previous studies have focused on mitral regurgitation (MR) or tricuspid regurgitation (TR) individually, without comparing their long‐term effects. The impact of staged transcatheter edge‐to‐edge repair (TEER) remains unclear.
European Journal of Heart Failure
JUNE 5, 2025
Cardiac resynchronization therapy (CRT) as an enabler for guideline-directed medical therapy (GDMT) in the Swedish Heart Failure Registry (SwedeHF). The figure summarizes the selection of the study population, changes in GDMTs and loop diuretic use/doses from baseline to 1.5-year follow-up in patients receiving versus not receiving CRT, and reports the results of the regression model for the association between CRT and GDMT optimization (i.e. increased vs. stable/decreased use/doses) and decreas
Journal of the American Heart Association
JUNE 5, 2025
Journal of the American Heart Association, Ahead of Print. BackgroundArrhythmia, particularly atrial fibrillation, is on the rise globally. While increased surveillance, aging populations, and other risk factors partially explain this rise, emerging risks such as extreme heat from climate change are underexplored.MethodsWe used Product Surveillance Registry by Medtronic (2016–2023) in the United States to examine patients with implantable cardioverter‐defibrillator or cardiac resynchronization t
Stroke Journal
JUNE 5, 2025
Stroke, Ahead of Print. BACKGROUND:GLP-1RAs (glucagon-like peptide-1 receptor agonists) have consistently demonstrated a protective effect against ischemic stroke. However, whether this benefit also extends to nontraumatic intracerebral hemorrhage (ICH) remains unknown. Given the blood pressure–lowering and anti-inflammatory properties of GLP-1RAs, we aimed to evaluate their potential impact on ICH risk in patients with type 2 diabetes.METHODS:We conducted a retrospective cohort study using glob
Medical Xpress - Cardiology
JUNE 5, 2025
Nearly one-third of people who adopted and adhered to a healthy diet did not lose any weight, but still reaped many health benefits, according to a new study led by researchers at Harvard T.H. Chan School of Public Health and Ben Gurion University, Israel.
HeartRhythm
JUNE 5, 2025
Cardiac stereotactic radiation therapy is a potential treatment for refractory ventricular tachycardia. We previously reported that carbon ion irradiation, with a higher dose concentration than X-rays, restored gap junction proteins and denervated excess sympathetic nerves in a rabbit heart model. However, histological analysis is limited to endpoint evaluations, requiring in vivo functional assessments.
Medical Xpress - Cardiology
JUNE 5, 2025
A new study provides a comprehensive overview of the current state of metabolomics research in arterial stiffness on a less explored aspect: early vascular aging, particularly in adolescents. The study offers hope for innovative approaches to vascular health.
Journal of the American Heart Association
JUNE 5, 2025
Journal of the American Heart Association, Ahead of Print. BackgroundWhether cognitive function declines before and shortly after new‐onset hypertension remains largely unknown.Methods and ResultsThis prospective study used data from wave 2 (2004) to wave 9 (2018) of the English Longitudinal Study of Aging of participants who were free of hypertension at baseline.
Journal of Cardiovascular Electrophysiology
JUNE 5, 2025
ABSTRACT Background Bipolar radiofrequency ablation has been increasingly used in cases with deep intramyocardial circuits refractory to unipolar ablation. Patients with Lamin A/C cardiomyopathy frequently exhibit VT arrhythmia originating from deep in the interventricular septum. Methods and Results We describe our use of bipolar ablation in a patient with nonischemic cardiomyopathy and Lamin A/C mutation for the treatment of a septal VT substrate with particular attention to pathology findings
Medical Xpress - Cardiology
JUNE 5, 2025
A new study from researchers at Mass General Brigham has found that a higher McCance Brain Care Score not only associates with the risk of brain-related conditions such as stroke, dementia, and depression but also strongly associates with developing cardiovascular disease and three common types of cancer. Their results are published in Family Practice.
American College of Cardiology
JUNE 5, 2025
The print publication of the ZENITH and SOUL trials originally presented and published online during ACC.25 in Chicago provides an additional platform for editorial commentary on their broader implication.
HCPLive
JUNE 5, 2025
Early results show efzofitimod's promise in treating systemic sclerosis-related interstitial lung disease, with significant skin improvement in patients.
Medical Xpress - Cardiology
JUNE 5, 2025
Blood clots can form in both arteries and veins. However, the reasons behind them differ, as do the consequences and the chances of preventing blood clots. In Sweden, almost half of all cases of venous thrombosis have a genetic explanation. A team of researchers from Lund University in Sweden has now discovered three gene variants that increase the risk of blood clots in the leg by up to 180%.
American College of Cardiology
JUNE 5, 2025
The ACC submitted written comments on June 4 to the Centers for Medicare and Medicaid Services (CMS) on the fiscal year (FY) 2026 Inpatient Prospective Payment System (IPPS) proposed rule.
The American Journal of Cardiology
JUNE 5, 2025
Publication date: Available online 5 June 2025 Source: The American Journal of Cardiology Author(s): Tatsuya Tokai, Masanobu Ishii, Yasuhiro Otsuka, So Ikebe, Taishi Nakamura, Kenichi Tsujita, Naoyuki Akashi, Hideo Fujita, Yasuhiro Nakano, Tetsuya Matoba, Takahide Kohro, Yusuke Oba, Tomoyuki Kabutoya, Kazuomi Kario, Yasushi Imai, Arihiro Kiyosue, Yoshiko Mizuno, Kotaro Nochioka, Masaharu Nakayama, Takamasa Iwai
Medical Xpress - Cardiology
JUNE 5, 2025
If you've ever cared for someone through illness, you know that healing doesn't just happen in hospitals or clinics. It happens at home—around dinner tables, during medication routines, and in countless quiet moments where someone chooses to stay, care and keep going.
Expert insights. Personalized for you.
115 
Let's personalize your content