Maternal Avocado Intake Tied to 44% Drop in Infant Food Allergy Risk
HCPLive
MAY 12, 2025
New research reveals that maternal avocado consumption during pregnancy significantly reduces the risk of infant food allergies.
Mon.May 12, 2025
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Albuminuria and cardiovascular outcomes in early-stage chronic kidney disease
Heart BMJ
MAY 12, 2025
Chronic kidney disease (CKD) represents a significant global health priority, affecting approximately 844 million adults (10% of the world population). 1 Beyond its implication for kidney health, CKD is inherently linked to cardiovascular disease (CVD), which is the leading cause of morbidity and mortality in this population. 2 The interplay between CKD and CVD is well documented, with mechanisms including shared risk factors, metabolic disturbances and systemic inflammation. 2 Albuminuria, a ma
Study Finds Underuse of Allergy Treatments in Teens with Pollen Allergic Rhinitis
HCPLive
MAY 12, 2025
A study shows that many children with pollen allergies face ongoing symptoms into adulthood, highlighting the need for better management.
Cardiovascular Magnetic Resonance for Quantification of Mitral Regurgitation
American College of Cardiology
MAY 12, 2025
Assessment of mitral regurgitation (MR) has traditionally been performed with echocardiography. However, echocardiography has known limitations including the lack of a single reliable parameter of severity, high inter- and intraobserver variability, and discordance between echocardiographic parameters in a given patient.
Bridging Innovation & Patient Care: The Growing Role of AI
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
IgE, Skin Prick Test Show Limited Diagnostic Utility for Pediatric Shrimp Allergy
HCPLive
MAY 12, 2025
Skin prick test showed limited symptom correlation and shrimp-specific IgE demonstrated greater diagnostic value than tropomyosin-specific IgE.
Age-specific prognosis of acute and steady minor elevations in cardiac troponin among non-acute myocardial infarction inpatients: a large real-world cohort study
Heart BMJ
MAY 12, 2025
Background The upper reference limit of normal (ULN) of cardiac troponin (cTn) for older adults can be higher than for young adults, while the same ULN is used for both older and young adults in the current clinical practice. Methods In this multicentre longitudinal cohort study, non-acute myocardial infarction (non-AMI) inpatients with at least two cTn concentrations hospitalised between 2013 and 2022 in the Tianjin Health and Medical Data Platform were included.
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Prognostic impact of albuminuria in early-stage chronic kidney disease on cardiovascular outcomes: a cohort study
Heart BMJ
MAY 12, 2025
Background The impact of early-stage chronic kidney disease (CKD) on cardiovascular outcomes, particularly when albuminuria is present, remains unclear. This study examined the associations between early CKD (stages 1 and 2) with and without albuminuria and the incidence of major adverse cardiovascular events (MACEs), heart failure (HF) and all-cause mortality.
Road to Boston Training Log | Race Recap!
Physiologically Speaking
MAY 12, 2025
Thank you all for following this journey through to the end. It still blows my mind that tens of thousands of people (some strangers, some friends) returned weekly to read about my training for the Boston Marathon. I sincerely hope something I shared has helped you train smarter or harder—whether for Boston or otherwise. That’s really the goal!
Case Report: a 28-year-old female with anomalous origin of the left coronary artery from the pulmonary artery syndrome presented as atrial fibrillation and pulmonary hypertension
Frontiers in Cardiovascular Medicine
MAY 12, 2025
Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) typically manifests in the first weeks of life. We report a 28-year-old woman with atrial fibrillation and pulmonary hypertension which were later found to be associated with ALCAPA syndrome. Despite a history free of traditional cardiovascular risk factors, her symptoms included exercise intolerance, palpitations, and an ischemic stroke.
Challenges in Treating ATTR-CM
HCPLive
MAY 12, 2025
Panelists discuss how treating patients with transthyretin amyloid cardiomyopathy (ATTR-CM) is challenging due to delayed diagnosis, disease heterogeneity, limited treatment options, multisystem involvement, genetic counseling needs, advanced organ damage, and patient adherence issues.
A higher preoperative total protein to albumin ratio independently predicted more severe postoperative acute kidney injury in patients with acute type A aortic dissection: a retrospective cohort study of 224 cases
Frontiers in Cardiovascular Medicine
MAY 12, 2025
ObjectivesIn this retrospective study, we investigated the incidence of postoperative acute kidney injury (AKI) and determined the predictors associated with AKI in patients underwent surgeries for acute type A aortic dissection (ATAAD).MethodsWe enrolled patients diagnosed with ATAAD and received operation. AKI was defined based on the Kidney Disease: Improving Global Outcomes criteria.
Dr. Adam Castano and Dr. C. Michael Gibson discuss: ACT-EARLY, a Phase 3 Study – Clinical Trial Results
Clinical Trial Results
MAY 12, 2025
Disclosures: Sponsored by BridgeBio Pharma, Inc
British Cardiovascular Society Annual Conference, 2025: message from Vice President Dr Shouvik Haldar and Chair of the Programme Committee, Professor Andrew Clark
Heart BMJ
MAY 12, 2025
On behalf of the President of the British Cardiovascular Society (BCS), Board, Executive and Programme Committee, we look forward to welcoming you at the BCS Annual Conference, 2–4 June 2025, held at Manchester Central. The theme of the conference this year is ‘The Risk Business’ We appreciate that this is a broad theme that could mean many things to many people, and indeed it gives us the bandwidth to discuss many aspects of cardiology from that perspective.
Systemic Symptoms of PR-10-Related Pollen Food Allergy Syndrome High in Pediatric Patients Surveyed
HCPLive
MAY 12, 2025
New findings reveal significant systemic symptoms in pediatric patients with PR-10-related pollen food allergy syndrome, highlighting the need for better management strategies.
Association between cardiometabolic index and cardiovascular disease: evidence From the NHANES 2007–2018
Frontiers in Cardiovascular Medicine
MAY 12, 2025
BackgroundAlthough the cardiometabolic index (CMI) has gained recognition as a new tool for evaluating metabolic health, the relationship between CMI and cardiovascular disease (CVD) remains unclear. This research sought to explore the potential association between CMI and CVD.MethodsParticipants from the 20072018 National Health and Nutrition Examination Survey (NHANES) were selected.
Centers of ATTR-CM and Family Counseling
HCPLive
MAY 12, 2025
Panelists discuss how referring patients with transthyretin amyloid (ATTR) to a specialty center or center of excellence ensures expert diagnosis, comprehensive care, advanced treatment options, and essential genetic counseling and family screening for improved outcomes.
Case Report: Thoracoscopic repair of a residual inferior sinus venosus-type defect with right lower pulmonary vein–inferior vena cava communication: intraoperative support using real-time 3D transesophageal echocardiography
Frontiers in Cardiovascular Medicine
MAY 12, 2025
BackgroundResidual venous defects after atrial septal defect (ASD) repair may remain asymptomatic for years and can be misinterpreted as partial anomalous pulmonary venous return. Accurate intraoperative imaging is essential to confirm the anatomy and guide repair, particularly in minimally invasive surgery.Case presentationA 28-year-old woman with no cardiopulmonary symptoms was referred after an abnormal electrocardiographic findings during a routine physical examination.
Corrigendum to Impella Versus Non-Impella for Nonemergent High-Risk Percutaneous Coronary Intervention The American Journal of Cardiology (2024) Volume 225, 15 August. Pages 4-9. DOI: 10.1016/j.amjcard.2024.05.038
The American Journal of Cardiology
MAY 12, 2025
Publication date: 15 August 2025 Source: The American Journal of Cardiology, Volume 249 Author(s): Pavan Reddy, Ilan Merdler, Cheng Zhang, Matteo Cellamare, Itsik Ben-Dor, Nelson L. Bernardo, Hayder D. Hashim, Lowell F.
Case Report: Deep sternal wound infection caused by Mycoplasma hominis after cardiac surgery
Frontiers in Cardiovascular Medicine
MAY 12, 2025
Deep sternal wound infection (DSWI) caused by Mycoplasma hominis after cardiac surgery is very rare and easily overlooked. This paper reports the case of a patient with DSWI after cardiac surgery. The patient had an unexplained fever postoperatively. On the seventh day after surgery, the incision opened, and there was pus leakage. On the 11th day after surgery, the pus culture indicated Mycoplasma hominis infection.
Dr. C. Michael Gibson and Dr. Vaduganathan discuss the pivotal role of the MRA Axis in the treatment of heart failure and other chronic disease states.
Clinical Trial Results
MAY 12, 2025
Skip to main content Clinical Trial Results Close Navigation Primary Navigation Home Slide Library This Week in Medicine® Past Videos About Contact Toggle Menu Search Dr. C. Michael Gibson and Dr. Vaduganathan discuss the pivotal role of the MRA Axis in the treatment of heart failure and other chronic disease states. Search for: Search Search archived content (2018 and prior) Search May 12, 2025 Uncategorized Article Navigation Dr.
Pressure-Derived Indices in the Left Main Coronary Artery: Insights From Comprehensive In Vivo Hemodynamic Studies of Diseased and Unobstructed Vessels
Circulation: Cardiovascular Interventions
MAY 12, 2025
Circulation: Cardiovascular Interventions, Ahead of Print. BACKGROUND:Pressure-based physiological evaluation of coronary artery disease is well established, but its application is limited in left main coronary artery (LMCA) disease. Our aim was to investigate whether pressure-based indices are comparable in the left anterior descending (LAD) and left circumflex artery (LCx) branches of the LMCA, and if discordance is due to differences in microvascular function in these territories.METHODS:Simu
Musclin Counteracts Skeletal Muscle Dysfunction and Exercise Intolerance in Heart Failure With Preserved Ejection Fraction
Circulation: Heart Failure
MAY 12, 2025
Circulation: Heart Failure, Ahead of Print. BACKGROUND:Exercise intolerance is a hallmark of heart failure with preserved ejection fraction (HFpEF) and is characterized by skeletal muscle (SkM) dysfunction with impaired oxidative capacity. To maintain oxidative capacity, the SkM secretes myokines such as musclin, which has been shown to potentiate NP (natriuretic peptide) signaling and induce PGC-1 (peroxisome proliferator-activated receptor- coactivator-1 alpha) signaling.
Diabetes mellitus aggravates myocardial inflammation and oxidative stress in aortic stenosis: a mechanistic link to HFpEF features
Cardiovascular Diabetology
MAY 12, 2025
Patients diagnosed with both aortic stenosis (AS) and diabetes mellitus (DM) encounter a distinctive set of challenges due to the interplay between these two conditions. This study aimed to investigate the eff.
Difference between central and peripheral adrenergic alpha receptors
Dr. S. Venkatesan MD
MAY 12, 2025
Understanding sympathetic nervous had never been easy. (It doesn’t in any way mean, we have mastered para-sympathetic !). As physicians and cardiologists, we are expected to know the updated adrenergic, dopaminergic, imidazoline receptors etc. We need to know at-least an overview of its current nomenclature, area of distribution, benefits of blocking and stimulating them.
Comparative Efficacy of Non-Statin Lipid-Lowering Therapies in Patients With Hypercholesterolemia at Increased Cardiovascular Risk: An Updated Network Meta-Analysis
Journal of Cardiovascular Pharmacology
MAY 12, 2025
Abstract: Hypercholesterolemia is associated with atherosclerotic cardiovascular disease (ASCVD), a leading cause of morbidity and mortality. Non-statin lipid-lowering therapies (LLTs) such as ezetimibe, proprotein convertase subtilisin/kexin type 9 (PCSK9) monoclonal antibodies (mAbs), bempedoic acid, and inclisiran have been recommended in clinical guidelines to treat patients with ASCVD and/or high cardiovascular (CV) risk having elevated low-density lipoprotein cholesterol (LDL-C) despite be
Changing Management of Focal Cerebral Arteriopathy of Childhood From 2010 to 2022
Stroke Journal
MAY 12, 2025
Stroke, Ahead of Print. BACKGROUND:The most common cause of arterial ischemic stroke in healthy children, focal cerebral arteriopathy (FCA), can progress rapidly over days with worsening brain injury. A 2017 retrospective Swiss study of corticosteroid treatment for FCA changed practice. To assess its impact, we compared the FCA cohorts from the 2 VIPS (Vascular Effects of Infection in Pediatric Stroke) prospective cohort studies.METHODS:The VIPS II study prospectively enrolled 205 children (29 d
The Contemporary Landscape of Cardiac Tamponade: Insights from the CATEO Study and the Evolving Pharmacologic Spectrum
Journal of Cardiovascular Pharmacology
MAY 12, 2025
No abstract available
Characterization of arrhythmia‐induced cardiomyopathy using magnetic resonance imaging in patients with persistent atrial fibrillation and left ventricular systolic dysfunction – insights from DECAAF II
European Journal of Heart Failure
MAY 12, 2025
Arrhythmia-induced cardiomyopathy (AIC) in left ventricular systolic dysfunction with atrial fibrillation (AF). HFrEF, heart failure with reduced ejection fraction; LVEF, left ventricular ejection fraction; MRI, magnetic resonance imaging. Abstract Aims Atrial fibrillation (AF) ablation in heart failure reduces mortality and hospitalizations and improves ejection fraction.
Get With the Guidelines-Heart Failure: Twenty Years in Review, Lessons Learned, and the Road Ahead
Circulation: Heart Failure
MAY 12, 2025
Circulation: Heart Failure, Ahead of Print. The Get With the Guidelines-Heart Failure program was developed in 2005 with the goal of bringing evidence-based guidelines in heart failure management into widespread clinical practice. The program includes workshops, webinars, tool kits, chart abstraction, performance benchmarking, and achievement awards to drive quality improvement at participating hospitals.
Must-know facts for women about heart, kidney and metabolic health
American Heart News - Heart News
MAY 12, 2025
DALLAS, May 12, 2025 Millions of women may be unknowingly living with risk factors for heart, kidney and metabolic disease interconnected conditions that together drive risk for cardiovascular disease, the leading cause of death among women,
Inpatient versus outpatient diagnosis of heart failure across the spectrum of ejection fraction: a population cohort study
Heart BMJ
MAY 12, 2025
Background Early heart failure (HF) diagnosis is crucial to ensure that optimal guideline-directed medical therapy (GDMT) is administered to reduce morbidity and mortality. Limited access to echocardiography could lead to a later diagnosis for patients, for example, during an HF hospitalisation (hHF). This study aimed to compare the incidence and outcomes of inpatient versus outpatient diagnosis of HF.
FDA Warns on Listeria Outbreak; HHS Plans More Firings; Sheep-Herding Cardiologist
Med Page Today
MAY 12, 2025
(MedPage Today) -- Note that some links may require registration or subscription. Ten people in California and Nevada were hospitalized in a listeria outbreak linked to prepared foods, the FDA said. And seven deaths were linked to the hepatitis.
Echocardiographic cardiac damage classification and clinical outcomes in atrial functional mitral regurgitation
Heart BMJ
MAY 12, 2025
Background Atrial functional mitral regurgitation (AFMR) arises from left atrial (LA) dilation, commonly associated with atrial fibrillation, and leads to progressive cardiac damage. This study evaluated the prognostic value of a novel echocardiographic cardiac damage classification system for patients with moderate or severe AFMR. Methods In a retrospective multicentre study, 1007 patients with AFMR were stratified into four groups based on echocardiographic findings: group 1, LA damage (dilati
Ep 204 High Risk Pulmonary Embolism Management
ECG Cases
MAY 12, 2025
There are many nuances in the management of patients with pulmonary embolism in cardiac arrest, peri-arrest or simply in shock: We need to optimize oxygenation and airway management, hemodynamic support, acid/base management, thrombolysis and/or catheter-directed therapies that Anton dives into with guest experts Dr. Lauren Westafer, Dr. Bourke Tillmann and Dr.
Peripartum cardiomyopathy : Does the fetal gender influence the Incidence and recurrence ?
Dr. S. Venkatesan MD
MAY 12, 2025
PPCM is a rare but an Important cardiac condition, that contribute to significant maternal and fetal morbidity and mortality.So many variables , triggers, back ground risks have been studied for decoding the pathogenesis of PPCM. Does the sex of baby inside the mothers womb, in any way influnce the incidence of PPCM ? When searched in the literarure, I found almost no data on this simple parameter.
GE HealthCare Unveils High-Performance MRI System
DAIC
MAY 12, 2025
tim.hodson Mon, 05/12/2025 - 11:22 May 12, 2025 GE HealthCarerecently unveiled Signa Sprint, an FDA 510(k) pending [1] ultra-premium wide bore 1.5T high-performance gradient MRI system, at the International Society for Magnetic Resonance in Medicine (ISMRM) 2025. This technology is designed to unlock advanced imaging possibilities in cardiology, oncology and other clinical and research areas.
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