Sun.Feb 02, 2025

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Sometimes a patient is fortunate to have a cardiac arrest

Dr. Smith's ECG Blog

Written by Pendell Meyers A man in his 60s presented with acute chest pain. Here is his triage ECG: What do you think? There is sinus rhythm with clear LVH. Leads V5-6 are suspicious for upright, enlarged T waves that are possibly inappropriate for the QRS complex, especially V6. But without a baseline for comparison, it would be difficult for me to say that it is specific and diagnostic for OMI.

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Predictive cardio-omics: translating single-cell multiomics into tools for personalized medicine

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 03 February 2025; doi:10.1038/s41569-025-01132-3 In this Clinical Outlook, we describe available multiomic studies in cardiovascular medicine, discuss the advantages and potential of multiomic techniques for clinical translation in cardiology, and highlight three promising aspects: the generation of unprecedented cellular atlases, the identification of composite diagnostic and prognostic biomarkers derived from integrative multiomic signatures, and th

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Dermatology Month in Review: January 2025

HCPLive

This review of January 2025 in dermatology news highlights new developments in the treatment of conditions such as psoriasis, alopecia areata, and atopic dermatitis.

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Patients with chronic heart failure and predominant left atrial versus left ventricular myopathy

Cardiovascular Ultrasound

Left atrial (LA) and ventricular (LV) functional impairment often co-exist in patients with heart failure (HF). However, some patients with HF have a disproportionate LA or LV dysfunction. We aimed to characte.

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Long-term outcomes of drainless anatomical lung resection surgery for pulmonary malignancies

Journal of Cardiothoracic Surgery

Drainless minimally invasive anatomical lung resection surgery for pulmonary malignancies is safe and feasible in terms of early postoperative outcomes. However, the quality of surgery in the long term remains.

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A case series of patients with cardiac amyloidosis evaluated at a Colombian university hospital

Frontiers in Cardiovascular Medicine

BackgroundIn Colombia, the characteristics of cardiac amyloidosis (CA)including wild-type transthyretin amyloidosis (ATTRwt), immunoglobulin light chain amyloidosis (AL), and genetic variant transthyretin amyloidosis (ATTRv)are underexplored.MethodsThis case series at a Colombian university hospital analyzed demographic, clinical, laboratory, radiological, and genetic data of CA patients diagnosed between 2018 and 2022.

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Stick With Baby Aspirin in Patients at High Risk for Preeclampsia

Med Page Today

(MedPage Today) -- AURORA, Colo. -- A higher dose of aspirin offered no significant benefit as preeclampsia prevention in high-risk patients, although those with multifetal gestations may have seen some gains, according to the ASAPP trial. The.

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Letter by Wang and Peng Regarding Article, “Virus-Induced Acute Respiratory Distress Syndrome Causes Cardiomyopathy Through Eliciting Inflammatory Responses in the Heart”

Circulation

Circulation, Volume 151, Issue 5 , Page e33-e34, February 4, 2025.

Article 49
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Can “mental muscle” help us recuperate?

Heart Sisters

Dr. Amy Morin: ‘Mental muscle’ helps us to focus on what we CAN control in life,instead of all the things we can’t.

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Measure Apolipoprotein B If We Believe What We Say About Precision Medicine

Circulation

Circulation, Volume 151, Issue 5 , Page 257-259, February 4, 2025.

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Performance of an Active Fixation Stylet-Driven Lead in Left Bundle Branch Area Pacing: Results from INSIGHT-LBBA

HeartRhythm

Left bundle branch area pacing (LBBAP) has been rapidly adopted despite a lack of leads with approved indications for LBBAP.

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A Win for Clinical Evidence: The First Head-to-Head Trial of Interventional Strategies for the Treatment of Pulmonary Embolism

Circulation

Circulation, Volume 151, Issue 5 , Page 274-276, February 4, 2025.

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Unusual hypertrophic cardiomyopathy: case report of an early onset wild-type ATTR amyloidosis accompanied by a chromosomal duplication involving the MYH6 and MYH7 gene

Frontiers in Cardiovascular Medicine

BackgroundHypertrophic cardiomyopathy (HCM) is characterized by an increased left ventricular (LV) wall thickness and LV mass. With an estimated prevalence of 1:200500, HCM is among the most common genetically determined cardiac diseases. Functionally, enhanced tissue stiffness and reduced elasticity, combined with diastolic dysfunction and myocardial fibrosis, can eventually lead to life-threatening arrhythmias and impaired blood flow through the heart chamber.

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Response by Grune and Nahrendorf to Letter Regarding Article, “Virus-Induced Acute Respiratory Distress Syndrome Causes Cardiomyopathy Through Eliciting Inflammatory Responses in the Heart”

Circulation

Circulation, Volume 151, Issue 5 , Page e35-e36, February 4, 2025.

Article 45
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What Lies Beneath: Provoking the QT to Identify Risk in Long QT syndrome

HeartRhythm

The complexion of phenotypically severe patients first described in the long QT syndrome (LQTS) registry have naturally evolved to a milder phenotype represented in the contemporary literature.1,2 We now recognize that up to 75% of genotype positive LQTS patients may have either concealed disease or a borderline abnormal QTc.3 This variable penetrance and expressivity has been illuminated via inherited arrhythmia clinics, accessible genetic testing and familial screening.