Medical Xpress - Cardiology

JUNE 16, 2025

A Swedish multi-center study led by researchers at Lund University shows a link between low fiber consumption and the presence of unstable or high-risk plaque in coronary arteries—the type of plaque that can trigger blood clots and cause heart attacks. The study also links dietary patterns to the composition of the plaques, i.e., how potentially dangerous they are.

Plaque 59

Plaque Blood Clot Diet Heart attacks 59

Circulation: Genomic and Precision Medicine

JUNE 16, 2025

Circulation: Genomic and Precision Medicine, Volume 18, Issue 3 , Page e004932, June 1, 2025. BACKGROUND:Genome-wide association studies have clustered candidate genes associated with atrial fibrillation (AF) into biological pathways reflecting different pathophysiological mechanisms. We investigated whether these pathways associate with distinct intermediate phenotypes and confer differing risks of cardioembolic stroke.METHODS:Three distinct subsets of AF-associated genetic variants, each repre

Genetic predisposition 40

Genetic predisposition Atrial Fibrillation Strokes Stroke 40

Medical Xpress - Cardiology

JUNE 16, 2025

Mass General Brigham researchers have developed a new AI tool in collaboration with the United States Department of Veterans Affairs (VA) to probe through previously collected CT scans and identify individuals with high coronary artery calcium (CAC) levels that place them at a greater risk for cardiovascular events. Their research, published in NEJM AI, showed the tool called AI-CAC had high accuracy and predictive value for future heart attacks and 10-year mortality.

Heart Disease 91

Heart Disease Heart attacks Heart Attack Research 91

Frontiers in Cardiovascular Medicine

JUNE 16, 2025

BackgroundHeart failure (HF) is a common and serious complication in maintenance hemodialysis (MHD) patients, significantly affecting their prognosis and quality of life. This study aims to identify risk factors for HF and evaluate targeted, risk-based nursing interventions.MethodsA total of 170 MHD patients admitted between January 2022 and January 2024 were divided into HF (n = 80) and non-HF groups (n = 90) based on the presence or absence of HF.

Risk Factors 52

Risk Factors Quality of Life Nursing Heart Failure 52

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

Patient Care

Journal of the American Heart Association

JUNE 16, 2025

Journal of the American Heart Association, Volume 14, Issue 12 , June 17, 2025. BackgroundAcute heart failure (AHF) is associated with high rehospitalization, morbidity, and mortality rates. Implementing medically tailored meal (MTM) interventions may help to optimize nutrition and improve outcomes for patients with AHF. This study aimed to explore facilitators and barriers to implementing an MTM intervention in a tertiary hospital.MethodsFrom August 2023 to October 2023, we conducted semistruct

Heart Failure 40

Heart Failure Hospital Nursing Research 40

Medical Xpress - Cardiology

JUNE 16, 2025

Exercising is healthy, but it also puts strain on the heart. During physical exertion, the protein troponin is released—a biomarker indicative of cardiac damage. New research from Radboudumc involving a thousand athletes shows that elevated troponin levels after exercise are not due to coronary atherosclerosis. This suggests that the cause of elevated troponin levels after exertion lies elsewhere.

Exercise 40

Exercise Atherosclerosis Biomarkers Research 40

Medical Xpress - Cardiology

JUNE 16, 2025

Gout flares are associated with cardiovascular events. Treating gout to target serum urate levels prevents flares, but whether such treatment can also prevent cardiovascular events is unknown.

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HeartRhythm

JUNE 16, 2025

Modulation of autonomic nervous system activation by ganglionated plexi (GP) ablation is considered a key component of atrial fibrillation (AF) treatment. Endocardial pulsed field ablation (PFA) has limited impact on epicardially located GPs due to their significant distance from the endocardium, whereas epicardial PFA delivery directly to GP sites may display antiarrhythmic effects by effective ablation of GPs with minimal collateral myocardial damage.

Ablation 40

Ablation Electrophysiology Atrial Fibrillation 40

Journal of the American Heart Association

JUNE 16, 2025

Journal of the American Heart Association, Volume 14, Issue 12 , June 17, 2025. BackgroundFailure to control blood pressure (BP) despite multiple prescribed antihypertensive medications (AHMs) is widespread and leads to worse clinical outcomes. Recent changes to BP targets in US clinical guidelines require an updated evaluation of BP control including evaluations of nonadherence and therapeutic inertia.MethodsWe leveraged clinical and insurance data sourced from >50 US health care organiz

Blood Pressure 45

Blood Pressure Hypertension Outcomes 45

European Journal of Heart Failure

JUNE 16, 2025

Liver stiffness measurement for central venous pressure assessment. AUC, area under the curve; BMI, body mass index; CI, confidence interval; CVP, central venous pressure; HF, heart failure; LSM, liver stiffness measurement; LVEF, left ventricular ejection fraction. Abstract Aims Central venous pressure (CVP) is an important variable in assessing heart failure (HF) patients.

Heart Failure 40

Heart Failure BMI Research Article 40

Society of Thoracic Surgeons - Congenital

JUNE 16, 2025

Skip to main content Top menu Thoracic Surgery Foundation The Annals of Thoracic Surgery Career Center STS National Database Learning Center CORA Sort by Relevance Newest Log In Join STS Main menu Education Education Ask CORA Online Learning E-Book Thoracic Surgical Curriculum 8-in-8 Video Series International Activities Educational Collaborations Credit Claiming Events Annual Meeting Calendar of Events Webinars Leadership Institute Resident Showdown News News Newsroom Blogs Podcasts Magazine Ne

Innovation 52

Innovation Education Cardiothoracic Webinar 52

DAIC

JUNE 16, 2025

tim.hodson Mon, 06/16/2025 - 11:27 June 13, 2025 — An international study has shown that targeted online education on atrial fibrillation (AF) for health professionals can improve guideline-adherent care. This cluster-randomized controlled trial, published in Nature Medicine 1 , was designed to test if structured online AF education for health professionals could improve the care that individual patients receive.

Education 52

Education Blood Clot Heart Rhythm Atrial Fibrillation 52

Journal of Cardiovascular Electrophysiology

JUNE 16, 2025

TYRX Pocket Health Study protocol and analysis. Patients with a previous TYRX implant returned for generator replacement. TYRX pockets had low inflammation, and device capsules were well-healed with predominantly mature collagen. No macroscopic calcification was observed. Compared to a historical control, capsule thickness and pocket adhesions were reduced.

Article 40

Article 40

Circulation: Cardiovascular Quality & Outcomes

JUNE 16, 2025

Circulation: Cardiovascular Quality and Outcomes, Ahead of Print. BACKGROUND:One-time atrial fibrillation (AF) screening trials in older adults have produced mixed results. In a secondary analysis of the VITAL-AF trial, we aimed to identify a subset of people in whom such screening is effective, using effect-based and risk-based approaches.METHODS:The VITAL-AF trial was a cluster-randomized trial of 1-time, 30-second single-lead ECG screening during primary care visits.

Atrial Fibrillation 40

Atrial Fibrillation Circulation Hospital Research 40

Journal of Cardiovascular Electrophysiology

JUNE 16, 2025

ABSTRACT Background Coronary Sinus Venous stenosis is rare; however, it is often encountered during left ventricular (LV) lead implantation, which is the cornerstone of cardiac resynchronization therapy (CRT). Plain balloon angioplasty and anchor balloon technique have been described for LV lead implantation in patients with venous stenosis and tortuous anatomy.

Angioplasty 40

Angioplasty Stenosis Anatomy Article 40

Frontiers in Cardiovascular Medicine

JUNE 16, 2025

ObjectiveThe objective of this research was to investigate the correlation between the Monocyte-to-high-density lipoprotein-cholesterol ratio (MHR), Neutrophil gelatinase-associated lipocalin (NGAL), and Angiotensin II (Ang II) with both short-term and long-term mortality rates in elderly patients with heart failure (HF).MethodsA retrospective cohort study was conducted, encompassing elderly HF patients hospitalized from 2020 to 2023.

Heart Failure 52

Heart Failure Biomarkers Cholesterol Research 52

DAIC

JUNE 16, 2025

tim.hodson Mon, 06/16/2025 - 10:46 June 11, 2025 — MorningStar Laboratories, LLC , a developer of precision diagnostic tests that address unmet clinical needs, has announced its SmartVascular Dx (SVDx) test (formally known as the PULS Cardiac test), designed to transform the early detection and management of vascular health, empowering healthcare providers to implement proactive strategies that significantly enhance patient outcomes.

Laboratory 52

Laboratory Biomarkers Technology Patient Care 52

European Journal of Heart Failure

JUNE 16, 2025

Abstract A better understanding of additional mechanisms of heart failure (HF) progression may allow a different and more complete phenotyping of the disease and identification of novel therapeutic targets. Persistent latent myocardial inflammation/immune activation in HF may represent an attempt to restore tissue homeostasis in the failing heart, where cardiomyocytes and immune cells undergo metabolic reprogramming, which allows them to deal with decreased availability of nutrients and oxygen.

Heart Failure 45

Heart Failure Outcomes 45

Circulation: Cardiovascular Interventions

JUNE 16, 2025

Circulation: Cardiovascular Interventions, Volume 18, Issue 6 , Page e015442, June 1, 2025.

Bicuspid/Mitral 40

Bicuspid/Mitral Aortic valve Cardiovascular Interventions TAVR 40

Frontiers in Cardiovascular Medicine

JUNE 16, 2025

IntroductionCalcitonin gene-related peptide (CGRP), particularly its alpha isoform, might play a role in restoring physiological cardiovascular functioning. While its involvement in acute myocardial infarction (AMI) pathophysiology has been suggested, human data remain scarce. This study analyzed circulating alpha-CGRP levels during AMI, comparing them to healthy controls (HC) and post-AMI resolution levels.MethodsA total of 26 AMI patients and 26 age- and sex-matched HC were recruited.

Myocardial Infarction 52

Myocardial Infarction Physiology Ischemia Research 52

Journal of the American Heart Association

JUNE 16, 2025

Journal of the American Heart Association, Volume 14, Issue 12 , June 17, 2025. BackgroundIncident atrial fibrillation (AF) is common among adults with kidney failure treated with maintenance dialysis and is associated with poor clinical outcomes. Limited data exist informing treatment of AF among patients on dialysis. We aimed to describe the use of rate‐control and antiarrhythmic medications for AF among patients on dialysis and associations of these medication use strategies with stroke and a

Atrial Fibrillation 40

Atrial Fibrillation Strokes Stroke Outcomes 40

All About Cardiovascular System and Disorders

JUNE 16, 2025

Echocardiogram illustrating regional wall motion abnormalities in coronary artery disease. The post Regional Wall Motion Abnormalities on Echocardiography appeared first on All About Cardiovascular System and Disorders.

Coronary Artery Disease 52

Coronary Artery Disease Echocardiogram General Cardiology 52

HeartRhythm

JUNE 16, 2025

Atrial fibrillation (AF) and heart failure (HF) frequently coexist, worsening outcomes. Catheter ablation (CA) is an established therapy, but the optimal timing remains unclear.

Atrial Fibrillation 45

Atrial Fibrillation Heart Failure Ablation Outcomes 45

DAIC

JUNE 16, 2025

tim.hodson Mon, 06/16/2025 - 16:17 June 16, 2025 – Penumbra, Inc. recently announced the completion of enrollment in the STORM-PE clinical trial. This prospective, multi-center randomized controlled trial enrolled 100 patients to evaluate computer assisted vacuum thrombectomy (CAVT) using Penumbra’s Lightning Flash plus anticoagulation, versus anticoagulation alone, for the treatment of acute intermediate-high risk pulmonary embolism (PE).

Blood Clot 52

Blood Clot Embolism Pulmonary Technology 52

Circulation: Heart Failure

JUNE 16, 2025

Circulation: Heart Failure, Ahead of Print.

Circulation 40

Circulation Article Heart Failure 40

Journal of the American Heart Association

JUNE 16, 2025

Journal of the American Heart Association, Volume 14, Issue 12 , June 17, 2025. BackgroundAlthough hypertension is prevalent in adults with moyamoya disease (MMD) and intracranial hemorrhage significantly worsens prognosis, the impact of hypertension on long‐term outcomes after encephaloduroarteriosynangiosis in hemorrhagic MMD remains unclear; this retrospective cohort study used propensity score matching to compare outcomes between hypertensive and nonhypertensive patients and preliminarily as

Hemorrhage 40

Hemorrhage Hypertension Blood Pressure Outcomes 40

Circulation: Cardiovascular Quality & Outcomes

JUNE 16, 2025

Circulation: Cardiovascular Quality and Outcomes, Ahead of Print.

Atrial Fibrillation 40

Atrial Fibrillation Circulation Outcomes 40

Journal of Clinical Investigation - Cardiology

JUNE 16, 2025

Myxomatous valve disease (MVD) is the most common form of cardiac valve disease in the developed world. A small fraction of MVD is syndromic and arises in association with matrix protein defects such as those in Marfan syndrome, but most MVD is acquired later in life through an undefined pathogenesis. The KLF2/4 transcription factors mediate endothelial fluid shear responses, including those required to create cardiac valves during embryonic development.

Transplant 80

Transplant 80

Circulation: Cardiovascular Quality & Outcomes

JUNE 16, 2025

Circulation: Cardiovascular Quality and Outcomes, Ahead of Print.

Stents 40

Stents Stent Circulation Outcomes 40

Journal of Clinical Investigation - Cardiology

JUNE 16, 2025

Bardet-Biedl syndrome (BBS), a ciliopathy characterized by obesity, hyperphagia, and learning deficits, arises from mutations in Bbs genes. Exacerbated symptoms occur with mutations in genes encoding the BBSome, a complex regulating primary cilia function. We investigated the mechanisms underlying BBS-induced obesity using a Bbs5-knockout (Bbs5–/–) mouse model.

Obesity 72

Obesity Circulation 72

Circulation: Cardiovascular Quality & Outcomes

JUNE 16, 2025

Circulation: Cardiovascular Quality and Outcomes, Ahead of Print.

Risk Factors 40

Risk Factors Article Cardiovascular Disease Circulation 40

Frontiers in Cardiovascular Medicine

JUNE 16, 2025

Kounis syndrome is an allergic myocardial ischemia syndrome triggered by various factors. Herein, we presented a case of a patient with Multiple Myeloma who developed chest pain as a result of lenalidomide use. The patient’s electrocardiogram (ECG) revealed ST-segment depression, along with elevated troponin I and eosinophils levels. Emergency coronary angiography identified thrombosis in the middle segment of the anterior descending branch of the left coronary artery.

Chest Pain 52

Chest Pain Myocardial Infarction Electrocardiogram Thrombosis 52

Circulation: Cardiovascular Quality & Outcomes

JUNE 16, 2025

Circulation: Cardiovascular Quality and Outcomes, Ahead of Print.

Risk Factors 40

Risk Factors Article Cardiovascular Disease Circulation 40

Journal of Clinical Investigation - Cardiology

JUNE 16, 2025

The complement system is a highly conserved and essential immune component with pivotal roles in innate and adaptive immunity. It is increasingly recognized that the complement system has a profound impact on disease. Current complement-targeting therapeutics for clinical use almost exclusively target the complement system in circulation. However, recent discoveries have demonstrated that complement is not only liver derived and plasma operative, but also synthesized and activated inside many ce

Innovation 58

Innovation Cancer Technology Circulation 58

Frontiers in Cardiovascular Medicine

JUNE 16, 2025

BackgroundPharmacomechanical catheter-directed thrombolysis (PCDT) is commonly used to treat acute deep venous thrombosis (DVT). The AngioJet Rheolytic Thrombectomy (ART) device is a widely used option. However, previous serious adverse events led to an FDA black-box warning. Limited large animal studies have assessed ART's efficacy and safety. We investigated the periprocedural outcomes and venous histomorphic impact of ART in a novel large animal acute DVT model.MethodsSix adult male Yorkshire

Thrombosis 52

Thrombosis Thrombolysis Outcomes Research 52

Journal of the American Heart Association

JUNE 16, 2025

Journal of the American Heart Association, Volume 14, Issue 12 , June 17, 2025.

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