Circulation: Genomic and Precision Medicine

JUNE 17, 2025

Circulation: Genomic and Precision Medicine, Ahead of Print. BACKGROUND:Clinical factors discriminate incident atrial fibrillation (AF) risk with moderate accuracy, with only modest improvement after incorporation of polygenic risk scores. Whether emerging large-scale proteomic profiling can augment AF risk estimation is unknown.METHODS:In the UK Biobank cohort, we derived and validated a machine learning model to predict incident AF risk using serum proteins (Pro-AF).

Atrial Fibrillation 40

Atrial Fibrillation Risk Factors Circulation 40

JAMA Cardiology

JUNE 17, 2025

This cohort study investigates if coronary computed tomography (CT) angiography is associated with better lifestyle behaviors, acceptance of preventive therapies, and improvement in risk factor modification compared with cardiovascular risk scoring.

Risk Factors 108

Risk Factors 108

CardiacWire

JUNE 17, 2025

By: Jimmy Su, Ph.D. Principal Scientist, Cardiovascular Ultrasound, Philips Jimmy Su, Ph.D. A new tool, Automated 3D Color Flow Quantification (3D Auto CFQ), removes the reliance on assumptions when quantifying mitral regurgitation and replaces it with a reliable and robust, AI-driven method that delivers precise measurement of mitral valve regurgitant volume (RVol) regardless of orifice shape and size.

Bicuspid/Mitral 52

Bicuspid/Mitral Ultrasound Download Cardiovascular Imaging 52

European Journal of Heart Failure

JUNE 17, 2025

Aims The European Heart Failure (HF) Survey was developed by the Heart Failure Association (HFA) of the European Society of Cardiology (ESC) to map HF management resources, reimbursement of drugs/devices for HF treatment, and structure and activities of HF professional and patient organizations. Methods and results The survey encompassed 43 ESC member countries.

Reimbursement 40

Reimbursement Heart Failure Heart Transplant Transplant 40

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

Patient Care

JAMA Cardiology

JUNE 17, 2025

We know how to prevent the majority of atherosclerotic cardiovascular disease (ASCVD), but this knowledge has not yet been translated into routine practice. Despite clear evidence that a healthy diet and physical activity improve cardiovascular outcomes, only a minority of adults adhere to these behaviors. Similarly, inexpensive, effective therapies like statins prevent ASCVD in individuals at high risk of an event, and yet the vast majority of eligible individuals are not taking these therapies

Diet 67

Diet Cardiovascular Disease Outcomes 67

Journal of Cardiovascular Pharmacology

JUNE 17, 2025

Takotsubo syndrome (TTS) is a stress-induced cardiomyopathy which is associated with important morbidity and in-hospital mortality. Microvascular dysfunction, inflammation and fibrosis may play crucial roles in TTS pathophysiology. Here we investigated the effect of methotrexate (MTX), an antiproliferative and immunosuppressive drug, on ventricular function in a rat model of Takotsubo syndrome.

Cardiac Function 40

Cardiac Function Cardiomyopathy Hospital Article 40

Circulation: Heart Failure

JUNE 17, 2025

Circulation: Heart Failure, Ahead of Print.

Heart Failure 40

Heart Failure Pulmonary Hypertension Circulation 40

JAMA Cardiology

JUNE 17, 2025

This prespecified secondary analysis of the Finerenone Trial to Investigate Efficacy and Safety Superior to Placebo in Patients With Heart Failure (FINEARTS-HF) examines the efficacy and safety of finerenone according to frailty status in patients with heart failure and mildly reduced or preserved ejection fraction.

Heart Failure 70

Heart Failure Preserved Ejection Fraction 70

Medical Xpress - Cardiology

JUNE 17, 2025

Cannabis use is linked to a doubling in the risk of dying from cardiovascular disease, with significantly heightened risks of having a stroke or acute coronary syndrome—sudden reduced or blocked blood flow to the heart—finds a pooled analysis of real-world data, published online in the journal Heart.

Cardiovascular Disease 105

Cardiovascular Disease Strokes Stroke 105

Journal of Cardiovascular Pharmacology

JUNE 17, 2025

Atherosclerosis (AS) is a chronic progressive disease that occurs in the inner walls of arteries. Endothelial dysfunction is a key component in the early stages of atherosclerosis. Unhealthy lifestyle factors (e.g., smoking), hypertension, hyperglycemia, and hyperlipidemia are important risk factors that may induce endothelial cell injury or even lead to cellular death.

Atherosclerosis 40

Atherosclerosis Risk Factors Hypertension Article 40

Medical Xpress - Cardiology

JUNE 17, 2025

Researchers at Children's Hospital of Philadelphia (CHOP) reported long-term clinical outcomes for the largest single center cohort of individuals who underwent complex reconstructive surgery for hypoplastic left heart syndrome as newborns. In this cohort, more than 30% survived without a transplant to at least 35 years of age.

Transplant 40

Transplant Research Hospital Outcomes 40

HeartRhythm

JUNE 17, 2025

His bundle (HB) pacing (HBP) is limited by higher capture thresholds at implant that may be unstable during follow-up, resulting in an increased risk of long-term lead-related complications compared to left bundle branch area pacing (LBBAP).1,2 Some studies suggest that in HBP, the appearance of a transient current of injury (COI) in the electrogram (EGM) after lead fixation indicates good lead fixation and can predict thresholds that are lower at implantation and remain stable during follow-up.

Outcomes 40

Outcomes 40

Hypertension Journal

JUNE 17, 2025

Hypertension, Volume 82, Issue 7 , Page 1246-1248, July 1, 2025.

Hypertension 40

Hypertension 40

Dr. Smith's ECG Blog

JUNE 17, 2025

Written by Willy Frick A man in his early 40s with prior anterior OMI s/p bare metal stent to LAD in 2014 presented with acute chest pain, nausea, dyspnea, and diaphoresis. He was brought in by EMS. His first ECG is shown: ECG 1 Obvious STEMI (+) OMI. What would you guess is the culprit? There is STE in V1 and V2 with lateral STD, a pattern known as precordial swirl , so.it should be LAD, right?

STEMI 113

STEMI Stents Stent Chest Pain 113

Hypertension Journal

JUNE 17, 2025

Hypertension, Volume 82, Issue 7 , Page e140-e140, July 1, 2025.

Hypertension 40

Hypertension 40

Journal of Cardiothoracic Surgery

JUNE 17, 2025

Early postoperative atrial fibrillation (early-POAF) is the most common complication after cardiac surgery. Although prior studies have demonstrated an association between early-POAF and late outcomes, it is q.

Atrial Fibrillation 59

Atrial Fibrillation Outcomes Research 59

Medical Xpress - Cardiology

JUNE 17, 2025

Researchers from the University of Southern Denmark and Odense University Hospital have studied tissue from patients with atherosclerosis. They found that many of the cells in the diseased tissue carried the same genetic alteration and appeared to originate from a single ancestral cell that had divided repeatedly—a pattern otherwise associated with tumor biology.

Atherosclerosis 92

Atherosclerosis Hospital Research 92

European Journal of Cardiovascular Nursing

JUNE 17, 2025

Abstract Aim Stroke survivors face significant challenges during their transition from hospital to home, impacting both their own well-being and that of their caregivers. Informal caregivers, often family members, assume substantial caregiving roles without professional training, leading to emotional strain and caregiver burden. Understanding the experiences of caregivers during this critical transitional period is essential for developing targeted interventions that alleviate burden and improve

Hospital 40

Hospital Strokes Stroke Outcomes 40

HCPLive

JUNE 17, 2025

The monoclonal antibody garadacimab-gxii offers once-monthly, citrate-free dosing to prevent hereditary angioedema attacks in patients aged ≥ 12 years.

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59

Cardiovascular Diabetology

JUNE 17, 2025

The diagnostic criteria for HFpEF remain inconsistently defined, further confounded by comorbidities such as obesity and type 2 diabetes mellitus (T2DM), which are thought to contribute to its pathogenesis via.

Obesity 52

Obesity Diabetes Biomarkers Research 52

All About Cardiovascular System and Disorders

JUNE 17, 2025

A brief review of normal colour Doppler echocardiogram in multiple views. The post Normal Colour Doppler Echocardiogram appeared first on All About Cardiovascular System and Disorders.

Echocardiogram 52

Echocardiogram General Cardiology 52

Medical Xpress - Cardiology

JUNE 17, 2025

Type 2 diabetes patients taking semaglutide, often sold as Ozempic or Wegovy, have a slightly lower risk of stroke compared to patients taking another diabetes drug—empagliflozin. International researchers studied data from 7,899 patients treated with semaglutide and 7,899 treated with empagliflozin to look for differences in the risk of death, heart attack, stroke, heart failure and an irregular heartbeat.

Diabetes 40

Diabetes Strokes Stroke Heart attacks 40

Journal of Cardiovascular Pharmacology

JUNE 17, 2025

To investigate the impact of antimiR-132, a miR-132 antisense inhibitor, on cardiac remodeling and function in a two-hit mouse model of heart failure with preserved ejection fraction (HFpEF), as well as its underlying mechanism. Male C57BL/6 mice were fed N(omega)-nitro-L-arginine methyl ester plus a high-fat diet to establish an HFpEF model, and then intraperitoneally injected with antimiR-132 or normal saline.

Preserved Ejection Fraction 40

Preserved Ejection Fraction Heart Failure Blood Pressure Diet 40

Medical Xpress - Cardiology

JUNE 17, 2025

Cancer and heart disease, two leading causes of death worldwide, may be more connected than we previously thought, according to a new UCLA Health study revealing that certain cardiac blood markers can strongly predict future cancer risk—even in people with no history or symptoms of heart disease.

Cancer 40

Cancer Heart Disease Biomarkers 40

Hypertension Journal

JUNE 17, 2025

Hypertension, Volume 82, Issue 7 , Page 1165-1166, July 1, 2025.

Hypertension 40

Hypertension Research 40

Dr. S. Venkatesan MD

JUNE 17, 2025

Covered stents are exclusively reserved for coronary artery perforations. Yes, that’s what we think. There has been limited exploration regarding the value of covering the complex lesions, which could prevent future coronary events. Currently covered stents are used almost exclusively in perforations rand rarely in very friable lesions. Ref : Kilic ID, Fabris E, Serdoz R, Caiazzo G, Foin N, Abou-Sherif S, Di Mario C.

Stents 52

Stents Stent Plaque Download 52

Cardiovascular Diabetology

JUNE 17, 2025

Despite established associations between insulin resistance (IR)-related indices and cardiometabolic diseases (CMDs), most studies are limited to single CMD outcomes. The study aimed to examine the influence o.

Outcomes 52

Outcomes Research 52

Stroke Journal

JUNE 17, 2025

Stroke, Ahead of Print. BACKGROUND:Understanding of sensorimotor reorganization following a stroke is still incomplete. This study examined how the neuromotor system of well-recovered patients with stroke achieves stable control of the redundant degrees of freedom in the upper limb through goal-directed reaching movements.METHODS:Thirteen right-handed individuals with left-hemispheric stroke and 13 age-, sex- and handedness-matched healthy controls participated in this cross-sectional study.

Strokes 40

Strokes Stroke Outcomes 40

DAIC

JUNE 17, 2025

SPONSORED CONTENT — Studycast is a comprehensive imaging workflow system that allows healthcare professionals to work from anywhere at any time. Available from Core Sound Imaging, Studycast provides an intuitive workflow from viewing images to creating reports to archiving exams. Its cloud-based system puts a comprehensive imaging workflow at your fingertips from any browser.

Document 88

Document Pediatrics Stenosis Aortic 88

HCPLive

JUNE 17, 2025

At SLEEP 2025, Kancherla emphasized the importance of using pediatric criteria to manage OSA in adolescents, warning that adult standards may overlook key developmental factors.

Pediatrics 76

Pediatrics 76

Circulation: Heart Failure

JUNE 17, 2025

Circulation: Heart Failure, Ahead of Print.

Circulation 40

Circulation Article Heart Failure 40

Hypertension Journal

JUNE 17, 2025

Hypertension, Volume 82, Issue 7 , Page e110-e113, July 1, 2025.

Hypertension 45

Hypertension 45

Med Page Today

JUNE 17, 2025

(MedPage Today) -- With newer data, clear lines could still be drawn between cannabis use and major adverse cardiovascular events (MACE), a meta-analysis confirmed. Based on two dozen pharmacoepidemiological studies published from 2016 to 2023.

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127

Hypertension Journal

JUNE 17, 2025

Hypertension, Volume 82, Issue 7 , Page e141-e141, July 1, 2025.

Hypertension 40

Hypertension 40

HCPLive

JUNE 17, 2025

News Media Podcasts State Of Sciences - Presentations Videos Webinars Multimedia Series CURE Connections® Insights Medcast Peer Exchange Peers & Perspectives Special Report Conferences Conference Coverage Conference Listing Partners CME/CE Resources Digital Supplements Interactive Tools Live Events Press Release Publications Sponsored Advisory Board Subscribe Choose Specialty Allergy Allergy Allergy Allergy Biosimilars Cardiology Cardiology Cardiology Cardiology Cardiology Cardiology Cardiol

Public Health 85

Public Health CME Transplant Pediatrics 85

Cardiovascular Diabetology

JUNE 17, 2025

Prediabetes represents the final stage on the glycemic spectrum before the onset of type 2 diabetes mellitus (T2DM), and delaying its progression offers a unique opportunity to address the growing T2DM epidemic.

Diabetes 82

Diabetes Research 82