Mon.Mar 17, 2025

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Researchers Link Infant Heart Defects, Childhood Cancer

DAIC

tim.hodson Mon, 03/17/2025 - 14:56 March 17, 2025 Being born with a heart defect may be associated with an increased cancer risk for babies and their moms, according to new research published today in the American Heart Associations flagship journal Circulation. According to the American Heart Association, the most common birth defects in the U.S. are forms of congenital heart defects (CHD).

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Newborns with heart defects may face a higher risk of developing childhood cancer

American Heart News - Heart News

Research Highlights: Newborns with congenital heart defects may have a higher risk of developing childhood cancer compared to children born without a heart abnormality. Congenital heart defects in newborns may also signal an elevated cancer risk for.

Cancer 114
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Statin Use Linked With Reduced Risks in Chronic Liver Disease

Med Page Today

(MedPage Today) -- Statin use in patients with chronic liver disease was associated with a reduced risk of hepatocellular carcinoma (HCC) and hepatic decompensation, researchers found. In a cohort of 16,501 individuals with chronic liver disease.

Research 113
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MOMENTUM Examines Hypercortisolism in Hypertension with Deepak L. Bhatt, MD

HCPLive

Initiation of the MOMENTUM clinical trial will explore the prevalence of endogenous hypercortisolism in patients with resistant hypertension.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Hair Loss: Another Wegovy Side Effect?

Med Page Today

(MedPage Today) -- A preprint study suggested that GLP-1 receptor agonists may be associated with hair loss, though only in women. Using a random sample of 16 million patients, researchers found that women who newly initiated semaglutide (Ozempic.

Research 112
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The Medical Sisterhood: Empower Hour at AAD 2025

HCPLive

Latanya Benjamin, MD, and Lindsay Ackerman, MD, joins The Medical Sisterhood in a live recording at AAD 2025 to discuss advocacy, mentorship, and empowerment.

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Distribution Variance of Focal Atrial Tachycardia Foci and Long‐Term Outcomes After Ablation: Experience From Two Chinese Centers

Journal of Cardiovascular Electrophysiology

Distribution Variance of Focal Atrial Tachycardia Foci and Long-Term Outcomes After Ablation. ABSTRACT Introduction The distribution of the origin of focal atrial tachycardia (FAT) in patients with different ages have not been clearly elucidated. We aimed to evaluate age differences in foci and factors influencing recurrence after radiofrequency catheter ablation in adult and juvenile patients with FAT.

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Blood Culture–Negative Endocarditis: A Scientific Statement From the American Heart Association

Journal of the American Heart Association

Journal of the American Heart Association, Ahead of Print. Blood culturenegative endocarditis has been associated with worse outcomes when compared with blood culturepositive endocarditis, because pathogendirected antimicrobial therapy and other management aspects have been difficult to achieve. Novel diagnostic tools, however, have changed the landscape of this syndrome and will likely improve patient outcomes.

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Replacing other snacks with pecans may improve cholesterol, diet quality

Medical Xpress - Cardiology

Switching daily snack foods to pecans improved cholesterol levels and enhanced overall diet quality, according to a new study by researchers in the Penn State Department of Nutritional Sciences.

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ACC’s First Concise Clinical Guidance Focuses on Evaluation and Management of Cardiogenic Shock

American College of Cardiology

The ACC has released its first Concise Clinical Guidance focused on best practices for the evaluation and management of patients with cardiogenic shock (CS).

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Uric acid shows potential as new stroke treatment in preclinical study

Medical Xpress - Cardiology

In a preclinical study, rodents treated with uric acid showed improved long-term outcomes after acute ischemic stroke. The findings suggest that the treatment may work as an add-on therapy to standard stroke treatments in humans. The study is published in Stroke.

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Spironolactone Gains Foothold in Acne Amid Unresolved Safety Questions

Med Page Today

(MedPage Today) -- With spironolactone (Aldactone) treatment for acne rising several-fold in recent decades, safety concerns persist for this off-label practice in understudied populations. A database of U.S. insurance claims showed that among.

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Antibiotics are the Most Common Drugs to Induce Anaphylaxis

HCPLive

A study found ceftriaxone was the most common drug to lead to anaphylaxis in children.

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Clinical management after surgical left atrial appendage exclusion

Journal of Cardiothoracic Surgery

Surgical left atrial appendage (LAA) closure is an increasingly utilized approach to mitigate the risk of cardioembolic stroke in patients with atrial fibrillation (AF). Consensus is lacking regarding optimal.

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FDA Accepts Finerenone sNDA for Heart Failure, Grants Priority Review

HCPLive

If approved, this indication targets the treatment of adult patients with heart failure with a left ventricular ejection fraction of 40%.

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8 cardiology first in 2025

Becker's Hospital Review - Cardiology

"Discover the latest groundbreaking achievements in cardiology, from the first robotic-assisted heart surgery in Ventura County to the world's first living mitr

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Clinical Quiz: Actinic Keratosis Follow-Up Recommendations from 2021 AAD Guidelines

HCPLive

This quiz, the fourth in this series, assesses your knowledge in post-AK treatment surveillance strategies, risk stratification, and more.

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ECU Health launches telecardiology clinic

Becker's Hospital Review - Cardiology

Greenville, N.C.-based Eastern Carolina University Health has established a new telecardiology program to provide patients with more accessible and convenient cardiovascular care.

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NHA’s Industry Outlook 2025: The Latest Trends in Allied Health Professions

Learning + Leading

Were thrilled to announce the release of NHAs 2025 Industry Outlook your guide to the trends and forecasts impacting healthcares future. In our report, we break down a number of key stats not only for each allied health role, but for the industry as a whole.

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AAD 2025 Phase 3 Recap: 7 Trials to Know

HCPLive

A recap of the 7 phase 3 trials presented during the 2025 AAD annual meeting's late-breaking sessions.

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Newborns with heart defects may face a higher risk of developing childhood cancer

Medical Xpress - Cardiology

Being born with a heart defect may be associated with an increased cancer risk for babies and their moms, according to new research published in Circulation.

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ECZTEND 2-Year Interim Findings: Takeaways and Considerations

HCPLive

Panelists discuss how the 2-year ECZTEND study found tralokinumab effective for atopic dermatitis, with 82.5% achieving EASI-75 and 59.8%, EASI-90. Common adverse effects (AEs) included upper respiratory tract infections, dermatitis, headache, and conjunctivitis. The treatment-emergent adverse event (TEAE) withdrawal rate was 1.6%.

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A Multifaceted Intervention to Mitigate the Adverse Cardiovascular Effects of Air Pollution: A Feasibility Randomized Controlled Trial

Journal of Cardiovascular Pharmacology

Air pollution is associated with excess thrombotic and cardiovascular events. However, clinical outcomes trials evaluating interventions to mitigate such adverse events in patients with atherosclerotic cardiovascular diseases (ASCVD) are lacking. This is a single-center, open-label, feasibility randomized controlled trial (RCT) conducted in adult patients with documented ASCVD.

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CKD Linked to Worse In-Hospital Outcomes After Radical Prostatectomy

HCPLive

Patients with CKD undergoing radical prostatectomy for prostate cancer experienced greater rates of adverse in-hospital outcomes.

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2025 STS/EACTS/LACES Latin America Cardiovascular Surgery Conference Exhibitor Prospectus

Society of Thoracic Surgeons - Congenital

2025 STS/EACTS/LACES Latin America Cardiovascular Surgery Conference Exhibitor Prospectus smccarthy Mon, 03/17/2025 - 10:41 Submit Your Application About the Conference The conference is a collaborative event hosted by STS, EACTS, and LACES, in partnership with the Sociedad Cientfica de Medicina Cardiovascular del Peru (SOCIMECAR). This 3-day event will bring together a world-class, international faculty to explore the latest developments and best practices in coronary artery disease, congenital

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Regular exercise pre-hospitalization is linked to better outcomes in heart failure, study shows

Medical Xpress - Cardiology

Heart failure is a major health concern, especially for aging populationsit significantly increases mortality rates, and severely impacts quality of life of those affected. Exercise therapy has been shown to be particularly effective for patients with heart failure. Previous research, however, has mainly examined the benefits of exercise after a diagnosis of heart failure.

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Can We Make the Next Step in Precision Risk Stratification of Dilated Cardiomyopathy?

Circulation: Cardiovascular Imaging

Circulation: Cardiovascular Imaging, Volume 18, Issue 3 , Page e018057, March 1, 2025.

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PCI for Surgically Ineligible Patients: Another Piece of the Jigsaw

Circulation: Cardiovascular Interventions

Circulation: Cardiovascular Interventions, Volume 18, Issue 3 , Page e015200, March 1, 2025.

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Efficacy of a gentamycin-collagen sponge to prevent infections in patients with an implantable cardioverter defibrillator undergoing device replacement or lead revision - results of a monocentric ICD registry observational study.

HeartRhythm

Despite the obvious benefits, the use of implantable cardioverter defibrillators (ICDs) is associated with serious complications, including infections. In particular, device replacement or revision procedures are associated with an increased risk of infection.

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Temporal Changes in Procedural Success and Clinical Outcomes of MTEER by Mechanism of MR: Analysis of the STS/TVT Registry

Circulation: Cardiovascular Interventions

Circulation: Cardiovascular Interventions, Volume 18, Issue 3 , Page e014819, March 1, 2025. BACKGROUND:With the expansion of indications for mitral transcatheter edge-to-edge repair into nondegenerative etiologies, it is unknown whether changes in technical success and clinical outcomes have occurred.METHODS:The Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy (STS/TVT) registry was analyzed from 2013 to 2023.

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Safety and Efficacy of a Novel Sealant‐Based Vascular Closure Device Following Electrophysiology Procedures: ReliaSeal Trial

Journal of Cardiovascular Electrophysiology

In a clinical trial of a novel sealant-based VCD to achieve hemostasis following endovascular procedures, patients randomized to receive the MYNX CONTROL VENOUS VCD had decreased TTH, TTA, and TDE, as compared to patients who received MC. ABSTRACT Background While manual compression (MC) remains the standard of care to achieve hemostasis, a novel vascular closure device (VCD) was designed to achieve faster hemostasis without compromising safety.

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Hydrochlorothiazide Is America's Most Popular Thiazide, But Should It Be?

Journal of the American Heart Association

Journal of the American Heart Association, Ahead of Print.

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Pharyngo‐Tympano‐Stapedial Variant of the Middle Meningeal Artery

Stroke: Vascular and Interventional Neurology

Stroke: Vascular and Interventional Neurology, Ahead of Print. The middle meningeal artery plays a vital role in supplying the cranial dura mater and is frequently targeted in some therapies. We describe another case of the pharyngotympanostapedial variant of the middle meningeal artery found incidentally in a patient undergoing a cerebral angiogram.

Stroke 40
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Targeted M‐Channel Activation in the Left Stellate Ganglion Protects Against Ischemia‐Induced Ventricular Arrhythmias in Canines

Journal of the American Heart Association

Journal of the American Heart Association, Ahead of Print. BackgroundAcute myocardial ischemia (AMI)triggered ventricular arrhythmias are closely linked to maladaptive sympathetic hyperactivity mediated via the left stellate ganglion (LSG). Although Mtype potassium channels regulate neuronal excitability and hold therapeutic potential for neurological disorders, their role in intrinsic LSG neurons during ischemia remains unexplored.

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Reevaluating Genetic Associations in Hypertrophic Cardiomyopathy

NEJM Journal Watch - Cardiology

An expert panel reclassifies the strength of association for several genotypes and identifies new candidate genes.

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Inter‐ and Intrahospital Price Variation for Common Cardiovascular Admission Diagnoses, Diagnostic Tests, and Therapeutic Procedures

Journal of the American Heart Association

Journal of the American Heart Association, Ahead of Print. BackgroundThe 2021 Price Transparency Rule was implemented to increase market competition, facilitate price shopping, and reduce prices and health care costs. We sought to measure inter and intrahospital variation in prices, measure price variation across payer types, and identify hospital characteristics associated with increased commercial prices for 16 common cardiovascular admission diagnoses, diagnostic tests, and therapeutic proced